Spolak-Bobryk Natalia, Niedoszytko Marek, Jassem Ewa, Chełmiñska Marta, Lange Magdalena, Majkowicz Mikołaj, Nedoszytko Bogusław, Borchet Judyta
Department of Allergology, Medical University of Gdansk, Gdansk, Poland.
Department and Clinic of Dermatology, Venereology and Allergology, Medical University of Gdansk, Gdansk, Poland.
Postepy Dermatol Alergol. 2022 Aug;39(4):688-696. doi: 10.5114/ada.2021.108433. Epub 2021 Sep 20.
Patients with mastocytosis have various clinical and psychological symptoms, for example, life-threatening anaphylactic reactions or anxiety, resulting in decreased quality of life (QoL).
To assess the clinical and psychological symptoms (such as depression, anxiety) as well as the quality of life and satisfaction with life in patients with mastocytosis.
The study group included 85 patients with mastocytosis (57 women and 28 men) treated at the Department of Allergology, Medical University of Gdansk, Poland. The measures employed in the study were the following: HADS-M, QLMS, and Cantril ladder.
Among clinical symptoms that occurred in the studied group, only allergy differentiated between the patients in terms of their QoL. Patients experiencing allergy symptoms presented lower QoL in the area of leisure time. The study findings indicate that 27.1% of participants experience anxiety, 12.9% experience depression, 15.3% present low satisfaction with the current life, and 10.6% express low satisfaction with life in the next 4 weeks. General QoL in mastocytosis, as well as the four areas of QoL in mastocytosis, remain positively correlated with anxiety, depression, and irritability, as well as negatively correlated with the satisfaction with current life and life in 4 weeks' time.
Patients who experience allergy symptoms have a lower level of QoL in the area of leisure time. Having more obstacles in various areas of life is associated with anxiety, depression, irritability, and low satisfaction with life. Learning how to overcome them can potentially improve the patients' QoL.
肥大细胞增多症患者有各种临床和心理症状，例如危及生命的过敏反应或焦虑，导致生活质量（QoL）下降。
评估肥大细胞增多症患者的临床和心理症状（如抑郁、焦虑）以及生活质量和生活满意度。
研究组包括在波兰格但斯克医科大学过敏科接受治疗的85例肥大细胞增多症患者（57名女性和28名男性）。研究中采用的测量方法如下：医院焦虑抑郁量表-情绪分量表（HADS-M）、生活质量量表（QLMS）和坎特里尔阶梯量表。
在研究组出现的临床症状中，只有过敏在患者的生活质量方面存在差异。出现过敏症状的患者在休闲时间方面的生活质量较低。研究结果表明，27.1%的参与者有焦虑情绪，12.9%有抑郁情绪，15.3%对当前生活满意度低，10.6%对未来4周的生活满意度低。肥大细胞增多症患者的总体生活质量以及肥大细胞增多症患者生活质量的四个领域与焦虑、抑郁和易怒呈正相关，与当前生活和4周后生活的满意度呈负相关。
出现过敏症状的患者在休闲时间方面的生活质量较低。生活各方面存在更多障碍与焦虑、抑郁、易怒和生活满意度低有关。了解如何克服这些障碍可能会改善患者的生活质量。
