Vicente-Rodriguez J, Chéchile G, Algaba F, Amaral J
Eur Urol. 1987;13(3):150-2. doi: 10.1159/000472761.
The data obtained from 2,272 random biopsies performed on cystocopically normal mucosa in 457 cases of primary bladder tumors, that did not undergo any previous treatment, are present. Dysplasia was found in 119 cases (26.04%) and carcinoma in situ in 100 cases (21.88%). The relationship between cancer in situ and tumoral grade was: G1, 4 of 76 (5.26%); G2, 33 of 225 (14.66%), and G3, 58 of 152 (38.16%). The relationship between cancer in situ and tumoral stage for superficial tumors (pTa-pT1) was 52 of 314 (16.56%), and for deep tumors (pT2, pT3, pT4), 42 of 109 (38.53%). In this least group of 109 cases, 53 cystectomies were performed and the diagnosis obtained by random biopsy and mapping of the surgical sample were correlated. A coincidence in both techniques was found in 77.36% of the cases.
本文呈现了对457例未经任何前期治疗的原发性膀胱肿瘤患者膀胱镜检查正常的黏膜进行2272次随机活检所获得的数据。119例（26.04%）发现发育异常，100例（21.88%）发现原位癌。原位癌与肿瘤分级的关系为：G1级，76例中有4例（5.26%）；G2级，225例中有33例（14.66%）；G3级，152例中有58例（38.16%）。浅表肿瘤（pTa - pT1）原位癌与肿瘤分期的关系为314例中有52例（16.56%），深部肿瘤（pT2、pT3、pT4）为109例中有42例（38.53%）。在这109例最少的病例组中，进行了53例膀胱切除术，并对随机活检结果与手术标本图谱诊断结果进行了相关性分析。两种技术在77.36%的病例中结果相符。
