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一名孕妇的罕见肺栓塞:原发性弥漫性肺动脉黏液纤维肉瘤病例报告。

Rare pulmonary embolism in a pregnant patient: A primary diffused pulmonary artery myxofibrosarcoma case report.

作者信息

Xiang Kanghui, Liu Lu, Li Hui-Jun, Zhang Guang-Wei

机构信息

Department of Medical Oncology, The First Hospital of China Medical University, Shenyang, China.

Key Laboratory of Anticancer Drugs and Biotherapy of Liaoning Province, The First Hospital of China Medical University, Shenyang, China.

出版信息

Front Oncol. 2022 Aug 25;12:956236. doi: 10.3389/fonc.2022.956236. eCollection 2022.

Abstract

A 37-year-old female patient presented with shortness of breath, cough, and chest pain complaints from the 12th week of her first pregnancy. At the 28th week, labor induction had to be performed because of severe dyspnea and hyoxemia. Thereafter, a diffused pulmonary embolism was detected by echocardiography and CT angiography, without histological diagnosis. Pulmonary endarterectomy was performed, and it was found during operation that a huge, lobular mass originated in the posterior wall and extended throughout the vasculature of both lungs, and a mucinous pellicle covered the entire pulmonary endothelium. Pathology revealed a low-grade myxofibrosarcoma with positive vimentin and SMA, partially positive CD-34.

摘要

一名37岁的女性患者在首次怀孕第12周时出现呼吸急促、咳嗽和胸痛症状。在第28周时,由于严重呼吸困难和低氧血症,不得不进行引产。此后,通过超声心动图和CT血管造影检测到弥漫性肺栓塞,但未进行组织学诊断。进行了肺动脉内膜剥脱术,术中发现一个巨大的小叶状肿块起源于后壁并延伸至双肺的整个脉管系统,并且一层黏液性薄膜覆盖了整个肺内皮。病理显示为低度黏液纤维肉瘤,波形蛋白和平滑肌肌动蛋白呈阳性,CD-34部分呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dabe/9452647/f323ea060930/fonc-12-956236-g001.jpg

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