Koto M, Miwa M, Tsuji K, Okamoto M, Adachi J
Jikken Dobutsu. 1987 Apr;36(2):151-6. doi: 10.1538/expanim1978.36.2_151.
The electrical impedance in the vagina (EIV) is significantly high in the proestrus stage compared with other stages of the estrous cycle in rats. Therefore, the EIV can be used to detect the optimum day for mating. The relation between the EIV and the conditions of the epithelial cell layer of vaginal mucosa were investigated. The EIV was at a high level (over 3,000 omega) in vaginas in the proestrus stage in either intact or excised vaginal mucus. But it decreased (under 3,000 omega) after the epithelium of the vaginal mucosa was removed. The EIV of ovariectomized rats was low, but increased after Estradiol administration. The cornification of the epithelial cell layer of the vaginal mucosa occurred concurrently with the high EIV in the proestrus stage and after Estradiol administration. This indicates that the cornification of the epithelial cell layer of the vaginal mucosa may cause the elevation of EIV in the proestrus stage, the optimum day for mating in the rats.
与大鼠发情周期的其他阶段相比，发情前期阴道的电阻抗（EIV）显著升高。因此，EIV可用于检测最佳交配日。研究了EIV与阴道黏膜上皮细胞层状况之间的关系。在完整或切除阴道黏液的情况下，发情前期阴道的EIV处于高水平（超过3000欧姆）。但在去除阴道黏膜上皮后，EIV降低（低于3000欧姆）。去卵巢大鼠的EIV较低，但在给予雌二醇后升高。阴道黏膜上皮细胞层的角质化在发情前期和给予雌二醇后与高EIV同时发生。这表明阴道黏膜上皮细胞层的角质化可能导致发情前期（大鼠最佳交配日）EIV升高。
