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上海市静安区成人白内障的患病率及危险因素

Prevalence and Risk Factors for Adult Cataract in the Jingan District of Shanghai.

作者信息

Hong Yingying, Sun Yang, Ye Xiaofang, Lu Yi, Xu Jianjiang, Xu Jianming, Ji Yinghong

机构信息

Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai 200031, China.

NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai 200031, China.

出版信息

J Ophthalmol. 2022 Aug 31;2022:7547043. doi: 10.1155/2022/7547043. eCollection 2022.

Abstract

PURPOSE

We report the prevalence of age-related cataract (ARC) in the Jingan district of Shanghai and analyze the risk factors for ARC to be better prepared for the increasing burden of cataracts as a significant cause of visual impairment worldwide.

METHODS

From March to June 2010, a population-based, cross-sectional study was conducted in a community selected by stratified cluster sampling in the Jingan district of Shanghai. Residents aged 40 and older were recruited and investigated by questionnaires and ophthalmic examination. Univariate and multivariate logistic regression models were used to evaluate the association of these risk factors with any cataract.

RESULTS

A total of 2894 subjects aged 40 years and above were included in our study. Nine hundred forty-eight people (32.8%) were diagnosed with cataract, including 845 with bilateral cataracts (29.2%) and 292 with moderate and severe visual impairment (low vision, 10.1%). There were significant differences in low vision among different age groups and gender (Χ  = 84.420,  < 0.001, Χ  = 7.696,  = 0.021). For any cataract, we found age (OR = 1.107, 95% CI: 1.094-1.120) and refractive error (OR = 1.352, 95% CI: 1.127-1.622) were independent risk factors.

CONCLUSION

The prevalence of cataract is estimated to be nearly one-third of the sample, increasing with age. We provided further evidence that age and refractive error are independent cataract risk factors.

摘要

目的

我们报告上海静安区年龄相关性白内障(ARC)的患病率,并分析ARC的危险因素,以便更好地应对白内障作为全球视力损害的重要原因所带来的日益增加的负担。

方法

2010年3月至6月,在上海静安区通过分层整群抽样选择一个社区进行基于人群的横断面研究。招募40岁及以上的居民,通过问卷调查和眼科检查进行调查。使用单因素和多因素逻辑回归模型评估这些危险因素与任何白内障的关联。

结果

我们的研究共纳入2894名40岁及以上的受试者。948人(32.8%)被诊断患有白内障,其中845人患有双侧白内障(29.2%),292人患有中度和重度视力损害(低视力,10.1%)。不同年龄组和性别之间的低视力存在显著差异(Χ  = 84.420,  < 0.001,Χ  = 7.696,  = 0.021)。对于任何白内障,我们发现年龄(OR = 1.107,95% CI:1.094 - 1.120)和屈光不正(OR = 1.352,95% CI:1.12

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