Li Yan-Jie, Pan Xin, Wang Cheng, He Ben
Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.
Front Cardiovasc Med. 2022 Aug 24;9:939297. doi: 10.3389/fcvm.2022.939297. eCollection 2022.
Infective endocarditis is a complication with high mortality in patients with congenital heart disease, particularly for those with bioprosthetic valve.
We report a case of a 54-year-old female with a history of tetralogy of Fallot who had been surgically repaired using a transannular patch due to severe pulmonary insufficiency with right heart enlargement and presented with worsening dyspnea. She had received transcatheter pulmonary valve implantation (TPVI) 5 years ago. Unfortunately, bioprosthesis-associated infective endocarditis occurred due to dental caries. Given persistent antibiotic medication, she became clinically stable with prosthesis functional recovery. However, dysfunctional bioprosthesis was still detected 3 years later, which was successfully treated by valve-in-valve TPVI with the help of modified buddy wire technique. At a 12-month follow-up after valve-in-valve TPVI, she was completely recovered with improved symptoms of heart failure.
This is the first report of valve-in-valve TPVI of a self-expandable valve in a degenerated self-expandable valve. The case highlights increased surveillance for infective endocarditis of transcatheter pulmonary valve should be emphasized. Subsequent valve-in-valve TPVI is an effective treatment for valve failure in defined conditions improving the hemodynamics.
感染性心内膜炎是先天性心脏病患者中一种死亡率较高的并发症,尤其是对于那些使用生物瓣膜的患者。
我们报告一例54岁女性,有法洛四联症病史,因严重肺功能不全伴右心扩大曾接受经环补片手术修复,现出现呼吸困难加重。她在5年前接受了经导管肺动脉瓣植入术(TPVI)。不幸的是,因龋齿发生了生物瓣膜相关感染性心内膜炎。经过持续抗生素治疗,她临床症状稳定,瓣膜功能恢复。然而,3年后仍检测到生物瓣膜功能障碍,借助改良导丝技术通过瓣中瓣TPVI成功治疗。在瓣中瓣TPVI术后12个月的随访中,她完全康复,心力衰竭症状改善。
这是首次关于在退化的自膨胀瓣膜中进行自膨胀瓣膜瓣中瓣TPVI的报告。该病例强调应加强对经导管肺动脉瓣感染性心内膜炎的监测。后续的瓣中瓣TPVI是在特定情况下治疗瓣膜功能衰竭、改善血流动力学的有效方法。