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病例报告:经导管肺动脉瓣中瓣植入术治疗感染性心内膜炎导致的衰败自膨式瓣膜

Case report: Transcatheter pulmonary valve-in-valve implantation in a deteriorated self-expandable valve caused by infective endocarditis.

作者信息

Li Yan-Jie, Pan Xin, Wang Cheng, He Ben

机构信息

Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai, China.

出版信息

Front Cardiovasc Med. 2022 Aug 24;9:939297. doi: 10.3389/fcvm.2022.939297. eCollection 2022.

Abstract

BACKGROUND

Infective endocarditis is a complication with high mortality in patients with congenital heart disease, particularly for those with bioprosthetic valve.

CASE SUMMARY

We report a case of a 54-year-old female with a history of tetralogy of Fallot who had been surgically repaired using a transannular patch due to severe pulmonary insufficiency with right heart enlargement and presented with worsening dyspnea. She had received transcatheter pulmonary valve implantation (TPVI) 5 years ago. Unfortunately, bioprosthesis-associated infective endocarditis occurred due to dental caries. Given persistent antibiotic medication, she became clinically stable with prosthesis functional recovery. However, dysfunctional bioprosthesis was still detected 3 years later, which was successfully treated by valve-in-valve TPVI with the help of modified buddy wire technique. At a 12-month follow-up after valve-in-valve TPVI, she was completely recovered with improved symptoms of heart failure.

CONCLUSION

This is the first report of valve-in-valve TPVI of a self-expandable valve in a degenerated self-expandable valve. The case highlights increased surveillance for infective endocarditis of transcatheter pulmonary valve should be emphasized. Subsequent valve-in-valve TPVI is an effective treatment for valve failure in defined conditions improving the hemodynamics.

摘要

背景

感染性心内膜炎是先天性心脏病患者中一种死亡率较高的并发症,尤其是对于那些使用生物瓣膜的患者。

病例摘要

我们报告一例54岁女性,有法洛四联症病史,因严重肺功能不全伴右心扩大曾接受经环补片手术修复,现出现呼吸困难加重。她在5年前接受了经导管肺动脉瓣植入术(TPVI)。不幸的是,因龋齿发生了生物瓣膜相关感染性心内膜炎。经过持续抗生素治疗,她临床症状稳定,瓣膜功能恢复。然而,3年后仍检测到生物瓣膜功能障碍,借助改良导丝技术通过瓣中瓣TPVI成功治疗。在瓣中瓣TPVI术后12个月的随访中,她完全康复,心力衰竭症状改善。

结论

这是首次关于在退化的自膨胀瓣膜中进行自膨胀瓣膜瓣中瓣TPVI的报告。该病例强调应加强对经导管肺动脉瓣感染性心内膜炎的监测。后续的瓣中瓣TPVI是在特定情况下治疗瓣膜功能衰竭、改善血流动力学的有效方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/186b/9449311/87c0ce6a2983/fcvm-09-939297-g0001.jpg

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