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儿童肌肉骨骼疼痛,我们应该考虑神经母细胞瘤吗?

Musculoskeletal pain in children, should we think about neuroblastoma?

作者信息

Sadeghi Payman, Habibi Zohreh, Ziaee Vahid

机构信息

Children's Medical Center, Pediatrics Center of Excellence Tehran Iran.

Department of Pediatrics Tehran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Sep 5;10(9):e6284. doi: 10.1002/ccr3.6284. eCollection 2022 Sep.

DOI:10.1002/ccr3.6284
PMID:36093442
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9445260/
Abstract

A 9-year-old girl with progressive right leg pain, distributed to the pelvis and lower spine, diminished muscle force, and tendon reflex, was worked up thoroughly. Thoracolumbar MRI showed a well-circumscribed homogenous enhanced extradural mass from L3-L4 to S1. After surgery, a firm extradural mass was resected, and the pathologic finding was a neuroblastoma.

摘要

一名9岁女孩,右腿进行性疼痛,疼痛分布至骨盆和下脊柱,肌力和腱反射减弱,接受了全面检查。胸腰椎磁共振成像(MRI)显示,从L3-L4至S1有一个边界清晰、均匀强化的硬膜外肿块。手术后,切除了一个质地坚硬的硬膜外肿块,病理检查结果为神经母细胞瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/320d6a0375a1/CCR3-10-e6284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/dd953953c042/CCR3-10-e6284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/56c0b63551e3/CCR3-10-e6284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/09cbf725dafb/CCR3-10-e6284-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/320d6a0375a1/CCR3-10-e6284-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/dd953953c042/CCR3-10-e6284-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/56c0b63551e3/CCR3-10-e6284-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/09cbf725dafb/CCR3-10-e6284-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20c9/9445260/320d6a0375a1/CCR3-10-e6284-g001.jpg

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本文引用的文献

1
Uncommon Presentation of Childhood Leukemia in Emergency Department: The Usefulness of an Early Multidisciplinary Approach.儿童白血病在急诊科的罕见表现:早期多学科方法的实用性
Pediatr Emerg Care. 2021 Jul 1;37(7):e412-e416. doi: 10.1097/PEC.0000000000001694.
2
Origin and initiation mechanisms of neuroblastoma.神经母细胞瘤的起源和起始机制。
Cell Tissue Res. 2018 May;372(2):211-221. doi: 10.1007/s00441-018-2796-z. Epub 2018 Feb 14.