Division of Pediatric Hematology/Oncology, Washington University in St. Louis School of Medicine, St. Louis, Missouri, USA.
Division of Pediatric Hematology/Oncology, Children's Hospital at Montefiore/Albert Einstein College of Medicine, New York, New York, USA.
Pediatr Blood Cancer. 2023 Jan;70(1):e29961. doi: 10.1002/pbc.29961. Epub 2022 Sep 12.
Sickle cell disease (SCD) requires coordinated, specialized medical care for optimal outcomes. There are no United States (US) guidelines that define a pediatric comprehensive SCD program. We report a modified Delphi consensus-seeking process to determine essential, optimal, and suggested elements of a comprehensive pediatric SCD center. Nineteen pediatric SCD specialists participated from the US. Consensus was predefined as 2/3 agreement on each element's categorization. Twenty-six elements were considered essential (required for guideline-based SCD care), 10 were optimal (recommended but not required), and five were suggested. This work lays the foundation for a formal recognition process of pediatric comprehensive SCD centers.
镰状细胞病（SCD）需要协调、专业的医疗护理，以达到最佳效果。美国目前尚无针对儿科综合性 SCD 项目的指南。我们报告了一项改良 Delphi 共识寻求过程，以确定综合性儿科 SCD 中心的基本、最佳和建议要素。19 名美国儿科 SCD 专家参与了此项研究。共识的定义是，对于每个要素的分类，有 2/3 的人达成一致。26 个要素被认为是必不可少的（基于指南的 SCD 护理所需），10 个是最佳的（推荐但并非必需的），5 个是建议的。这项工作为儿科综合性 SCD 中心的正式认可过程奠定了基础。
