Zhu Miao, Zhang She, Shi Qingqing, Sun Xing, Zhang Xiaowei, Wang Haibo, Liu Yanqing, Sun Mei
Department of Integrated Chinese and Western Medicine, Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou 225001, China.
The Key Laboratory of Syndrome Differentiation and Treatment of Gastric Cancer of the State Administration of Traditional Chinese Medicine, Department of Integrated Chinese and Western Medicine, Yangzhou University, Yangzhou 225001, China.
Heliyon. 2022 Aug 30;8(9):e10448. doi: 10.1016/j.heliyon.2022.e10448. eCollection 2022 Sep.
A 52-year-old woman complained of inguinal lymph node enlargement, low fever and night sweats for 20 days. After pathological biopsy and metagenomic sequencing, she was diagnosed as having infection. Her lymph nodes were accompanied by multiple ulcers in the affected area and sinus formation. Azithromycin was administered according to the Sanford Guide to Antimicrobial Therapy 2020, combined with wound repair and partial resection of inguinal lymph nodes. The patient showed good recovery after the operation. In all, lymphadenitis associated with infection is difficult to diagnose. Lymphadenitis with suppuration and sinus formation needs multidisciplinary consultation. When the causal pathogen is unknown, metagenomic sequencing is recommended for a definite diagnosis.
一名52岁女性主诉腹股沟淋巴结肿大、低热及盗汗20天。经病理活检和宏基因组测序后,她被诊断为感染。其淋巴结伴有受累区域多处溃疡及窦道形成。根据《2020年桑福德抗微生物治疗指南》给予阿奇霉素治疗,同时结合伤口修复及腹股沟淋巴结部分切除术。术后患者恢复良好。总之,与该感染相关的淋巴结炎难以诊断。伴有化脓及窦道形成的淋巴结炎需要多学科会诊。当致病病原体不明时,建议进行宏基因组测序以明确诊断。