Composite group, Mechanical Systems Engineering, Swiss Federal Laboratories for Materials Science and Technology-Empa, 8600 Dübendorf, Switzerland.
Department of Chemistry, University of Mumbai, Santacruz (E), Mumbai 400098, India.
Dalton Trans. 2022 Oct 4;51(38):14686-14699. doi: 10.1039/d2dt01405j.
We report the controlled growth of biologically active compounds: gold nanoparticles (AuNPs) in various shapes, including their green synthesis, characterization, and studies of their applications towards biological, degradation and recycling. Using spectroscopic methods, studies on responsive binding mechanisms of AuNPs with biopolymers herring sperm deoxyribonucleic acid (hsDNA), bovine serum albumin (BSA), dyes degradation study, and exquisitely gold separation studies/recovery from nanowaste, COVID-19 testing kits, and pregnancy testing kits are discussed. The sensing ability of the AuNPs with biopolymers was investigated various analytical techniques. The rate of degradation of various dyes in the presence and absence of AuNPs was studied by deploying stirring, IR, solar, and UV-Vis methods. AuNPs were found to be the most active cytotoxic agent against human breast cancer cell lines such as MCF-7 and MDAMB-468. Furthermore, an economical process for the recovery of gold traces from nanowaste, COVID-19 detection kits, and pregnancy testing kits was developed using inexpensive and eco-friendly α-cyclodextrin sugar. This method was found to be easy and safest in comparison with the universally accepted cyanidation process. In the future, small gold jewelry makers and related industries would benefit from the proposed gold-recycling process and it might contribute to their socio-economic growth. The methodologies proposed are also beneficial for trace-level forensic investigation.
各种形状的金纳米粒子（AuNPs），包括它们的绿色合成、表征以及在生物、降解和回收方面的应用研究。使用光谱方法，研究了 AuNPs 与生物聚合物（如鲱鱼精子脱氧核糖核酸（hsDNA）、牛血清白蛋白（BSA））的响应性结合机制，研究了染料降解、从纳米废物、COVID-19 检测试剂盒和妊娠检测试剂盒中进行精细的金分离研究/回收。利用各种分析技术研究了 AuNPs 与生物聚合物的传感能力。通过搅拌、IR、太阳能和 UV-Vis 方法研究了各种染料在存在和不存在 AuNPs 时的降解速率。发现 AuNPs 是对人类乳腺癌细胞系（如 MCF-7 和 MDAMB-468）最有效的细胞毒性剂。此外，还开发了一种使用廉价且环保的α-环糊精糖从纳米废物、COVID-19 检测试剂盒和妊娠检测试剂盒中回收金痕迹的经济工艺。与普遍接受的氰化工艺相比，该方法被发现既简单又安全。在未来，小金饰制造商和相关行业将受益于拟议的黄金回收工艺，这可能有助于他们的社会经济增长。所提出的方法也有利于痕量法医调查。
