The University of Queensland, Brisbane, Queensland, Australia.
Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Low Urin Tract Symptoms. 2022 Nov;14(6):427-433. doi: 10.1111/luts.12463. Epub 2022 Sep 13.
To evaluate the national trends in minimally invasive surgical therapies (MIST) for overactive bladder (OAB) in Australia over the past decade.
Annual MIST data were extracted using the Australian Medicare Benefit Schedule (MBS) on intravesical botulinum toxin (BTX), sacral nerve modulators (SNM) and percutaneous tibial nerve stimulators (PTNS) performed between 2010 and 2021. Population-adjusted rates of these procedures were compared in relation to individual states and against the introduction of various OAB drugs during the intervening years.
The overall national utilization of MIST for OAB has increased over the last decade. The data reflect a rapid uptake in PTNS over the last 2 years following its introduction compared to the relatively steady increase in BTX and SNM over the past decade. There was minimal difference in SNM lead and generator placement, suggesting perhaps the conversion of trial SNM to permanent SNM has been relatively stable across the years. In contrast, there was an increase in PTNS maintenance in the following years following the initial rise in the PTNS treatment initiation. The introduction of various OAB drugs in the market did not seem to significantly affect the pattern of MIST uptake.
Despite the introduction of various OAB drugs, the overall MIST has increased steadily over the last decade, especially with PTNS. Further exploration into the motivators for specific MIST and cost-benefit analysis of these MIST for OAB is warranted.
评估过去十年中澳大利亚治疗膀胱过度活动症(OAB)的微创外科治疗(MIST)的全国趋势。
使用澳大利亚医疗保险福利计划(MBS)在 2010 年至 2021 年期间提取膀胱内肉毒杆菌毒素(BTX)、骶神经调节剂(SNM)和经皮胫神经刺激器(PTNS)的年度 MIST 数据。比较这些程序在各州的人口调整率,以及与干预年间引入的各种 OAB 药物的关系。
过去十年中,澳大利亚治疗 OAB 的整体 MIST 使用率有所增加。数据反映了在过去两年中,PTNS 的采用速度较快,而 BTX 和 SNM 在过去十年中则相对稳定地增加。SNM 导联和发生器的放置差异不大,这表明在过去的几年中,试验性 SNM 向永久性 SNM 的转换可能相对稳定。相比之下,在初始 PTNS 治疗启动后的随后几年中,PTNS 维持治疗有所增加。市场上引入的各种 OAB 药物似乎并没有显著影响 MIST 的采用模式。
尽管引入了各种 OAB 药物,但过去十年中整体 MIST 稳步增加,尤其是 PTNS。有必要进一步探讨特定 MIST 的动机,并对这些 MIST 治疗 OAB 的成本效益进行分析。