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高良姜果胶多糖:一种有效的乳化剂,用于构建基于乳液的高良姜类黄酮递送系统。

Pectin-type polysaccharide from galangal: An efficient emulsifier to construct the emulsion-based delivery system for galangal flavonoids.

机构信息

School of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510641, China.

School of Food Science and Engineering, South China University of Technology, Guangzhou 510641, China; Guangdong Food Green Processing and Nutrition Regulation Technology Research Center, Guangzhou 510641, China; Chaozhou Branch of Chemistry and Chemical Engineering Guangdong Laboratory, Chaozhou 521000, China.

出版信息

Int J Biol Macromol. 2022 Nov 30;221:644-652. doi: 10.1016/j.ijbiomac.2022.09.051. Epub 2022 Sep 12.

DOI:10.1016/j.ijbiomac.2022.09.051
PMID:36099993
Abstract

Galangal is rich in flavonoids and polysaccharides but underutilized. In this study, galangal flavonoids and polysaccharides (GP-HN and GP-UN) were obtained by segmented extraction, used for chemical composition determination/structural characterization, and constructed for the emulsion delivery system. The results showed that galangin accounted for 71.45 % of total flavonoids. GP-HN and GP-UN were prepared by enzymatic-assisted high-temperature and ultrasonic extraction, which were low-molecular-weight pectin-type polysaccharides mainly constructed by galacturonic acid, galactose, and arabinose. GP-UN was the best emulsifier due to interfacial activities, emulsifying properties, interfacial resistance to bile salts displacement abilities, and anti-lipid digestion abilities of GPs. GP-UN emulsion could stably deliver flavonoids. This study presented a method for orderly reorganizing flavonoids and polysaccharides, guiding for utilization of whole bioactive components in galangal.

摘要

高良姜富含类黄酮和多糖,但未得到充分利用。本研究采用分段提取法获得高良姜类黄酮和多糖(GP-HN 和 GP-UN),用于化学成分测定/结构表征,并构建乳液输送系统。结果表明,高良姜中的总类黄酮中 71.45%为高良姜素。GP-HN 和 GP-UN 采用酶辅助高温超声提取法制备,主要由半乳糖醛酸、半乳糖和阿拉伯糖构成的低分子量果胶型多糖。由于具有界面活性、乳化性能、界面耐胆汁盐置换能力和抗脂解能力,GP-UN 是最佳的乳化剂。GP-UN 乳液能稳定地输送类黄酮。该研究提出了一种有序重组类黄酮和多糖的方法,为高良姜中全生物活性成分的利用提供了指导。

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