Kómár J, Szalay M, Szél I
Fortschr Neurol Psychiatr. 1987 Jun;55(6):201-2.
A transient myasthenic syndrome confirmed by EMG after taking large doses of beta blocking agent is reported. Data on similar complications have not been found in the literature. Theories trying to explain the myasthenic, myopathic effect of the beta-blocking agents are reviewed. In the opinion of the authors the quinidine-like membrane stabilising effect played a role in their case, although the possibility of the direct effect of the drug on the neurotransmitters cannot be excluded either.
据报道,服用大剂量β受体阻滞剂后经肌电图证实出现短暂性肌无力综合征。文献中未发现类似并发症的数据。本文回顾了试图解释β受体阻滞剂致肌无力、肌病作用的相关理论。作者认为,奎尼丁样膜稳定作用在他们的病例中起了作用,尽管也不能排除药物对神经递质的直接作用。