Takebe T, Murashima Y, Suga T, Satoh M
Hokkaido Igaku Zasshi. 1987 May;62(3):461-8.
We carried out through questionnaires the second survey on the epidemiology and the clinical features of chronic pancreatitis in Hokkaido district. Chronic pancreatitis was diagnosed in 258 patients in 19 hospitals during the period April 1977 to December 1984. The ratio of male cases to females was 2.7:1.0 and the average age was 53.9. Alcoholic abuse, observed in 55% of the patients, was a main causative factor. A half of the patients was diagnosed on the basis of pancreatogram and/or image of the pancreas (ultrasonogram and computed tomogram). The incidence of chronic pancreatitis in the second survey was about fourfold over that diagnosed during the period January 1970 to March 1977 in the first survey. Such an increasing number of the patients with chronic pancreatitis in Hokkaido district was considered to be resulted from the difference between two surveys in epidemiological aspects and diagnostic criteria. The proportion of female patients and alcoholic patients was calculated to be increasing. The frequency of the patients diagnosed in a relatively early stage was supposed to be also increasing, because in the second survey a new item (pancreatogram, ultrasonogram and computed tomogram) was added to the diagnostic criteria (histological evidence, pancreatic calcification and definitive disturbance of exocrine pancreatic function) in the first survey. Based on whether alcoholic abuse was causative factor or not, the patients were divided into two groups and the clinical manifestations of both groups were compared.(ABSTRACT TRUNCATED AT 250 WORDS)
我们通过问卷调查对北海道地区慢性胰腺炎的流行病学和临床特征进行了第二次调查。在1977年4月至1984年12月期间,19家医院共诊断出258例慢性胰腺炎患者。男女病例之比为2.7:1.0,平均年龄为53.9岁。55%的患者存在酒精滥用,这是主要致病因素。一半的患者是根据胰管造影和/或胰腺影像(超声检查和计算机断层扫描)确诊的。第二次调查中慢性胰腺炎的发病率约为第一次调查(1970年1月至1977年3月)期间确诊病例的四倍。北海道地区慢性胰腺炎患者数量的增加被认为是由于两次调查在流行病学方面和诊断标准上的差异所致。女性患者和酒精性患者的比例预计在增加。在相对早期被诊断出的患者频率也可能在增加,因为在第二次调查中,诊断标准(第一次调查中的组织学证据、胰腺钙化和外分泌胰腺功能的明确紊乱)中增加了一项新内容(胰管造影、超声检查和计算机断层扫描)。根据酒精滥用是否为致病因素,将患者分为两组并比较了两组的临床表现。(摘要截断于250字)