School of Nursing, School of Public Health, Yangzhou University, Yangzhou, China.
Nurs Open. 2023 Feb;10(2):424-434. doi: 10.1002/nop2.1364. Epub 2022 Sep 13.
To review and analyse the evidence on the efficacy and safety of non-pharmacological interventions for preterm infants to relieve endotracheal suctioning (ES) pain.
A systematic review per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
Six databases were searched with a retrieval strategy. Parallel and crossover randomized controlled trials reporting non-pharmacological interventions for relieving ES pain in preterm infants were identified from inception to 1 September 2021. The protocol was published in PROSPERO (CRD42021276058).
Ten studies were retrieved, including nine different non-pharmacological interventions. Seven studies reported that non-pharmacological interventions in relieving pain were more effective than conventional care during ES, and three trials reported its safety. Due to the heterogeneity of pain assessment tools, time of assessment and population, only Facilitated tucking had sufficient evidence that it is a safe and effective non-pharmacological intervention.
回顾和分析非药物干预缓解经气管吸引(ES)疼痛的早产儿的疗效和安全性证据。
按照系统评价和荟萃分析的首选报告项目进行系统评价。
从开始到 2021 年 9 月 1 日,使用检索策略在六个数据库中进行搜索。确定了从早产儿缓解 ES 疼痛的非药物干预的平行和交叉随机对照试验。该方案已在 PROSPERO(CRD42021276058)中发布。
检索到 10 项研究,包括 9 种不同的非药物干预措施。7 项研究报告称,与常规护理相比,非药物干预在 ES 期间更能有效缓解疼痛,3 项试验报告了其安全性。由于疼痛评估工具、评估时间和人群的异质性,只有促进襁褓法有足够的证据表明它是一种安全有效的非药物干预措施。