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“更安全的阿片类药物分发”作为应对阿片类药物死亡危机的一项基本公共卫生干预措施——广泛实施的考量、选择及示例

'Safer opioid distribution' as an essential public health intervention for the opioid mortality crisis - Considerations, options and examples towards broad-based implementation.

作者信息

Fischer Benedikt, Lee Angelica, Vojtila Lenka

机构信息

Schools of Population Health and Pharmacy, Faculty of Medical and Health Sciences, University of Auckland, 85 Park Road, Grafton, Auckland, New Zealand.

Department of Psychiatry, University of Toronto, 250 College Street, Toronto, Ontario, Canada.

出版信息

Public Health Pract (Oxf). 2020 May 26;1:100016. doi: 10.1016/j.puhip.2020.100016. eCollection 2020 Nov.

DOI:10.1016/j.puhip.2020.100016
PMID:36101693
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9461513/
Abstract

•Canada experiences excessive opioid mortality, mainly from toxic opioid exposure.•Many interventions have been implemented, but are limited in reach and impact.•'Safer opioid distribution' (SOD) is a crucial preventive measure for overdose.•SOD needs to be implemented for a large, 'at-risk' opioid user population.•Other community-based public health interventions may guide SOD organization.

摘要

•加拿大存在过量阿片类药物致死情况，主要源于接触有毒阿片类药物。

•已实施多项干预措施，但覆盖范围和影响有限。

•“更安全的阿片类药物分发”（SOD）是预防过量用药的关键措施。

•需要针对大量“高危”阿片类药物使用者群体实施SOD。

•其他基于社区的公共卫生干预措施可能为SOD的组织工作提供指导。

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本文引用的文献

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Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study.阿片类激动剂治疗与阿片类药物过量公共卫生紧急情况下的死亡率之间的关系：基于人群的回顾性队列研究。
BMJ. 2020 Mar 31;368:m772. doi: 10.1136/bmj.m772.
2
Correlations between opioid mortality increases related to illicit/synthetic opioids and reductions of medical opioid dispensing - exploratory analyses from Canada.与非法/合成阿片类药物相关的阿片类药物死亡率增加与医疗用阿片类药物配给减少之间的相关性——来自加拿大的探索性分析。
BMC Public Health. 2020 Jan 31;20(1):143. doi: 10.1186/s12889-020-8205-z.
3
Applying principles of injury and infectious disease control to the opioid mortality epidemic in North America: critical intervention gaps.将伤害与传染病控制原则应用于北美阿片类药物致死流行情况：关键干预差距
J Public Health (Oxf). 2020 Nov 23;42(4):848-852. doi: 10.1093/pubmed/fdz162.
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Injectable opioid agonist treatment for opioid use disorder: a national clinical guideline.用于阿片类物质使用障碍的注射用阿片类激动剂治疗：一项国家临床指南。
CMAJ. 2019 Sep 23;191(38):E1049-E1056. doi: 10.1503/cmaj.190344.
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'Communities are attempting to tackle the crisis': a scoping review on community plans to prevent and reduce opioid-related harms.“社区正在努力应对这场危机”：关于预防和减少阿片类药物相关危害的社区计划的范围界定审查
BMJ Open. 2019 Sep 12;9(9):e028583. doi: 10.1136/bmjopen-2018-028583.
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