Department of Biomedical Engineering, Fatih Sultan Mehmet Vakif University, Istanbul, Turkey.
Biomed Tech (Berl). 2022 Sep 14;67(6):429-442. doi: 10.1515/bmt-2022-0123. Print 2022 Dec 16.
The utilization of nanotechnology in regenerative medicine has been globally proven to be the main solution to many issues faced with tissue engineering today, and the theoretical and empirical investigations of the association of nanomaterials with stem cells have made significant progress as well. For their ability to self-renew and differentiate into a variety of cell types, stem cells have become popular candidates for cell treatment in recent years, particularly in cartilage and Ocular regeneration. However, there are still several challenges to overcome before it may be used in a wide range of therapeutic contexts. This review paper provides a review of the various implications of nanomaterials in tissue and cell regeneration, the stem cell and scaffold application in novel treatments, and the basic developments in stem cell-based therapies, as well as the hurdles that must be solved for nanotechnology to be used in its full potential. Due to the increased interest in the continuously developing field of nanotechnology, demonstrating, and pinpointing the most recognized and used applications of nanotechnology in regenerative medicine became imperative to provide students, researchers, etc. who are interested.
纳米技术在再生医学中的应用已被全球证明是解决当今组织工程所面临的许多问题的主要方法,纳米材料与干细胞的结合的理论和经验研究也取得了重大进展。近年来,由于其自我更新和分化为多种细胞类型的能力,干细胞已成为细胞治疗的热门候选者,特别是在软骨和眼部再生方面。然而,在广泛的治疗环境中使用之前,仍然有几个挑战需要克服。本文综述了纳米材料在组织和细胞再生中的各种应用,新型治疗中干细胞和支架的应用,以及基于干细胞的治疗的基础发展,以及为了充分发挥纳米技术的潜力而必须解决的障碍。由于人们对不断发展的纳米技术领域越来越感兴趣,因此有必要展示和指出纳米技术在再生医学中的最被认可和使用的应用,以便为有兴趣的学生、研究人员等提供参考。