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社会剥夺与全膝关节置换术的使用、不良事件和患者报告的结局指标有关吗?一项系统评价。

Is Social Deprivation Associated With Usage, Adverse Events, and Patient-reported Outcome Measures in Total Joint Arthroplasty? A Systematic Review.

机构信息

Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA.

出版信息

Clin Orthop Relat Res. 2023 Feb 1;481(2):239-250. doi: 10.1097/CORR.0000000000002394. Epub 2022 Sep 14.

Abstract

BACKGROUND

To capture various social determinants of health, recent analyses have used comprehensive measures of socioeconomic disadvantage such as deprivation and vulnerability indices. Given that studies evaluating the effects of social deprivation on total joint arthroplasty (TJA) have yielded mixed results, a systematic review of this relationship might help answer questions about usage, complications, and results after surgery among patients in different socioeconomic groups and help guide targeted approaches to ensure health equity.

QUESTIONS/PURPOSES: We asked: How is social deprivation associated with TJA (1) usage, (2) adverse events including discharge deposition and length of stay, and (3) patient-reported outcome measures (PROMs)?

METHODS

A comprehensive review of the PubMed, EBSCO host, Medline, and Google Scholar electronic databases was conducted to identify all studies that evaluated social deprivation and TJA between January 1, 2000, and March 1, 2022. Studies were included if they evaluated comprehensive measures of socioeconomic deprivation rather than individual social determinants of health. Nineteen articles were included in our final analysis with a total of 757,522 patients. In addition to characteristics of included studies (such as patient population, procedure evaluated, and utilized social deprivation metric), we recorded TJA usage, adverse events, and PROM values as reported by each article. Two reviewers independently evaluated the quality of included studies using the Methodological Index for Nonrandomized Studies (MINORS) tool. The mean ± SD MINORS score was 13 ± 1 of 16, with higher scores representing better study quality. All the articles included are noncomparative studies. Given the heterogeneity of the included studies, a meta-analysis was not performed and results were instead presented descriptively.

RESULTS

Although there were inconsistencies among the included articles, higher levels of social deprivation were associated with lower TJA usage even after controlling for various confounding variables. Similarly, there was agreement among studies regarding higher proportion of nonhome discharge for patients with more social deprivation. Although there was limited agreement across studies regarding whether patients with more social deprivation had differences in their baseline and postoperative PROMs scores, patients with more social deprivation had lower improvements from baseline for most of the included articles.

CONCLUSION

These findings encourage continued efforts focusing on appropriate patient education regarding expectations related to functional improvement and the postoperative recovery process, as well as resources available for further information and social support. We suggest linking patient data to deprivation measures such as the Area Deprivation Index to help encourage shared decision-making strategies that focus on health literacy and common barriers related to access. Given the potential influence social deprivation may have on the outcome and utilization of TJA, hospitals should identify methods to determine patients who are more socially deprived and provide targeted interventions to help patients overcome any social deprivation they are facing. We encourage physicians to maintain close communication with patients whose circumstances include more severe levels of social deprivation to ensure they have access to the appropriate resources. Additionally, as multiple social deprivation metrics are being used in research, future studies should identify a consistent metric to ensure all patients that are socially deprived are reliably identified to receive appropriate treatment.

LEVEL OF EVIDENCE

Level III, therapeutic study.

摘要

背景

为了全面了解健康的各种社会决定因素,最近的分析采用了剥夺和脆弱性指数等综合的社会经济劣势衡量标准。鉴于评估社会剥夺对全膝关节置换术(TJA)影响的研究结果存在差异,对这种关系进行系统综述可能有助于解答不同社会经济群体患者在手术使用、并发症和结果方面的问题,并有助于指导有针对性的方法,以确保健康公平。

问题/目的:我们想知道:社会剥夺与 TJA(1)使用、(2)不良事件,包括出院安置和住院时间,以及(3)患者报告的结果测量(PROM)之间存在怎样的关联?

方法

对 PubMed、EBSCOhost、Medline 和 Google Scholar 电子数据库进行了全面检索,以确定 2000 年 1 月 1 日至 2022 年 3 月 1 日期间评估社会剥夺与 TJA 之间关系的所有研究。如果研究评估了综合的社会经济剥夺衡量标准,而不是个体的社会决定因素,则将其纳入研究。我们最终分析纳入了 19 篇文章,共纳入了 757522 名患者。除了纳入研究的特征(如患者人群、评估的手术程序和使用的社会剥夺指标)外,我们还记录了每项研究报告的 TJA 使用情况、不良事件和 PROM 值。两位评审员使用非随机研究方法学指数(MINORS)工具独立评估了纳入研究的质量。MINORS 评分的平均值±标准差为 13±1 分(满分 16 分),得分越高表示研究质量越好。所有纳入的文章均为非对照研究。由于纳入研究的异质性,因此未进行荟萃分析,而是以描述性方式呈现结果。

结果

尽管纳入的文章之间存在不一致,但即使在控制了各种混杂变量后,社会剥夺程度较高与 TJA 使用减少相关。同样,大多数研究也一致认为,社会剥夺程度较高的患者非家庭出院的比例更高。尽管纳入的研究之间在社会剥夺程度较高的患者是否存在基线和术后 PROM 评分差异方面存在不一致,但大多数研究都认为,社会剥夺程度较高的患者基线到术后的改善程度较低。

结论

这些发现鼓励继续努力,重点关注针对功能改善和术后恢复过程的适当患者教育,以及提供进一步信息和社会支持的资源。我们建议将患者数据与剥夺指标(如区域剥夺指数)联系起来,以帮助鼓励以健康素养和获取方面的常见障碍为重点的共同决策策略。鉴于社会剥夺可能对 TJA 的结果和使用产生影响,医院应确定方法来确定社会剥夺程度较高的患者,并提供针对性的干预措施,以帮助患者克服所面临的任何社会剥夺问题。我们鼓励医生与社会剥夺程度较高的患者保持密切沟通,以确保他们能够获得适当的资源。此外,由于研究中使用了多种社会剥夺指标,未来的研究应确定一致的指标,以确保所有面临社会剥夺的患者都能被可靠地识别出来,从而获得适当的治疗。

证据水平

III 级,治疗性研究。

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