铝镁抗酸剂与酮硅灵在人体中的生物利用度
Aluminum-magnesium antacids and the bioavailability of ketoscilium in man.
作者信息
Widmer P S, Sonnenberg A, Koelz H R, Gazzaniga A, Brändli H, Blum A L
出版信息
Arzneimittelforschung. 1979;29(1):148-50.
PMID:36104
Abstract
The bioavailability of the gastric secretory inhibitor 3-hydroxy-8-(p-phenylphenacyl)-1 alphaH, 5 alphaH-tropanium bromide (-)-tropate (ketoscilium, Ulcesium) is not affected by a single dose of an aluminum-magnesium antacid although binding occurs in vitro.
摘要
胃分泌抑制剂3-羟基-8-（对苯基苯甲酰）-1αH，5αH-托烷溴化物（-）-托品酸盐（凯托西利姆，乌尔斯西姆）的生物利用度不受单剂量铝镁抗酸剂的影响，尽管在体外会发生结合。
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