• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Pyridostigmine-induced coronary artery spasm in early-onset myasthenia gravis: a case presentation and review of the literature.吡斯的明诱发早发型重症肌无力患者冠状动脉痉挛：病例报告及文献复习。
BMJ Case Rep. 2022 Sep 14;15(9):e249819. doi: 10.1136/bcr-2022-249819.
2
Diplopia in a patient presenting with "blurred vision": a case report.患者主诉“视物模糊”伴复视：病例报告。
J Med Case Rep. 2023 Sep 8;17(1):402. doi: 10.1186/s13256-023-04089-4.
3
The effect of use of pyridostigmine and requirement of vecuronium in patients with myasthenia gravis.吡啶斯的明的使用对重症肌无力患者维库溴铵需求的影响。
J Postgrad Med. 2003 Oct-Dec;49(4):311-4; discussion 314-5.
4
Coronary spastic angina after the administration of intravenous immunoglobulin in myasthenia gravis: a case report.静脉注射免疫球蛋白治疗重症肌无力后发生冠状动脉痉挛性心绞痛：病例报告。
BMC Neurol. 2020 Aug 28;20(1):319. doi: 10.1186/s12883-020-01901-2.
5
Coronary vasospasm secondary to hypercholinergic crisis: an iatrogenic cause of acute myocardial infarction in myasthenia gravis.高胆碱能危象继发的冠状动脉痉挛：重症肌无力急性心肌梗死的医源性病因。
Int J Cardiol. 2005 Sep 1;103(3):335-7. doi: 10.1016/j.ijcard.2004.06.026.
6
Comparative effects of plasma exchange and pyridostigmine on respiratory muscle strength and breathing pattern in patients with myasthenia gravis.血浆置换与吡啶斯的明对重症肌无力患者呼吸肌力量和呼吸模式的比较性影响。
Thorax. 1995 Oct;50(10):1080-6. doi: 10.1136/thx.50.10.1080.
7
Successful desensitization protocol for pyridostigmine in a 12 year old patient with myasthenia gravis.一名12岁重症肌无力患者成功的溴吡斯的明脱敏方案。
Turk J Pediatr. 2023;65(2):326-329. doi: 10.24953/turkjped.2022.386.
8
Myasthenia gravis in a young Papuan woman.一名年轻巴布亚女性的重症肌无力
P N G Med J. 1993 Sep;36(3):243-5.
9
Myasthenia gravis presentation and treatment variations: A case study approach.重症肌无力的表现及治疗差异：病例研究方法
J Am Assoc Nurse Pract. 2019 May;31(5):319-323. doi: 10.1097/JXX.0000000000000177.
10
Hypophonia as only presenting symptom in myasthenia gravis - a diagnostic dilemma in poor countries: a case report.以发声微弱为重症肌无力唯一表现症状——贫困国家中的诊断难题：一例病例报告
J Med Case Rep. 2019 Mar 2;13(1):48. doi: 10.1186/s13256-019-1970-6.

引用本文的文献

1
The relationship between early-onset coronary artery disease and familial hypercholesterolemia: a cohort study based on the Hakka population in Meizhou, China.早发性冠状动脉疾病与家族性高胆固醇血症的关系：基于中国梅州客家人群的队列研究。
Am J Transl Res. 2024 Sep 15;16(9):4564-4576. doi: 10.62347/NQFJ9713. eCollection 2024.
2
Perioperative cardiac risks in myasthenia gravis.重症肌无力患者围手术期的心脏风险
World J Clin Cases. 2024 May 6;12(13):2147-2150. doi: 10.12998/wjcc.v12.i13.2147.

本文引用的文献

1
International Consensus Guidance for Management of Myasthenia Gravis: 2020 Update.国际重症肌无力管理共识指南：2020 年更新版。
Neurology. 2021 Jan 19;96(3):114-122. doi: 10.1212/WNL.0000000000011124. Epub 2020 Nov 3.
2
Rare Case of Iatrogenic Myocardial Infarction Induced by Use of Pyridostigmine.使用吡啶斯的明诱发医源性心肌梗死的罕见病例。
Cureus. 2020 Aug 18;12(8):e9849. doi: 10.7759/cureus.9849.
3
Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome.重症肌无力和兰伯特-伊顿肌无力综合征
Continuum (Minneap Minn). 2016 Dec;22(6, Muscle and Neuromuscular Junction Disorders):1978-2005. doi: 10.1212/CON.0000000000000415.
4
Non-coronary myocardial infarction in myasthenia gravis: Case report and review of the literature.重症肌无力患者的非冠状动脉性心肌梗死：病例报告及文献综述
World J Cardiol. 2013 Jul 26;5(7):265-9. doi: 10.4330/wjc.v5.i7.265.
5
Mechanisms of coronary artery spasm.冠状动脉痉挛的机制。
Circulation. 2011 Oct 18;124(16):1774-82. doi: 10.1161/CIRCULATIONAHA.111.037283.
6
Acute myocardial infarction with normal coronary arteries: role of coronary artery spasm and arrhythmic complications.冠状动脉正常的急性心肌梗死：冠状动脉痉挛及心律失常并发症的作用
Int J Cardiol. 2007 Apr 12;117(1):3-5. doi: 10.1016/j.ijcard.2006.10.001. Epub 2006 Dec 19.
7
Coronary vasospasm secondary to hypercholinergic crisis: an iatrogenic cause of acute myocardial infarction in myasthenia gravis.高胆碱能危象继发的冠状动脉痉挛：重症肌无力急性心肌梗死的医源性病因。
Int J Cardiol. 2005 Sep 1;103(3):335-7. doi: 10.1016/j.ijcard.2004.06.026.
8
Clinical characteristics of female patients with coronary spastic angina: comparison with male patients.冠状动脉痉挛性心绞痛女性患者的临床特征：与男性患者的比较。
Jpn Circ J. 2000 Jun;64(6):416-20. doi: 10.1253/jcj.64.416.
9
Influence of calcium antagonist drugs in myasthenia gravis in the elderly.钙拮抗剂药物对老年重症肌无力的影响。
J Clin Pharm Ther. 1998 Oct;23(5):399-401. doi: 10.1046/j.1365-2710.1998.00172.x.
10
Induction of coronary artery spasm by acetylcholine in patients with variant angina: possible role of the parasympathetic nervous system in the pathogenesis of coronary artery spasm.乙酰胆碱诱发变异型心绞痛患者冠状动脉痉挛：副交感神经系统在冠状动脉痉挛发病机制中的可能作用。
Circulation. 1986 Nov;74(5):955-63. doi: 10.1161/01.cir.74.5.955.

吡斯的明诱发早发型重症肌无力患者冠状动脉痉挛：病例报告及文献复习。

Pyridostigmine-induced coronary artery spasm in early-onset myasthenia gravis: a case presentation and review of the literature.

机构信息

Division of Neurology, Department of Medicine, Sunpasithiprasong Hospital, Ubon Ratchathani, Thailand.

Division of Cardiology, Department of Medicine, Sunpasithiprasong Hospital, Ubon Ratchathani, Thailand.

出版信息

BMJ Case Rep. 2022 Sep 14;15(9):e249819. doi: 10.1136/bcr-2022-249819.

DOI:10.1136/bcr-2022-249819
PMID:36104035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9476139/
Abstract

We present a case of pyridostigmine-induced coronary artery spasm in a woman with early-onset myasthenia gravis (MG) who suffered from acute chest discomfort a few days after pyridostigmine dose up-titration. Twelve-lead ECG demonstrated ST-segment elevation in inferior limb leads together with sinus arrest. Sublingual nitrate was immediately given, which rapidly relieved her symptoms concomitantly with the resolution of abnormal ECG findings. Coronary angiography showed normal coronary arteries reflecting the transient nature of the disease. A small dose of pyridostigmine was rechallenged under close monitoring in the coronary care unit and reproduced her chest discomfort. After the substitution of pyridostigmine with immunosuppressive agents and prescription of long-acting nitrate, she had no recurrence of chest discomfort, as well as well-controlled MG symptoms.

摘要

我们报告了一例吡啶斯的明诱发的冠状动脉痉挛病例，患者为一名早发型重症肌无力（MG）女性，在吡啶斯的明剂量滴定增加几天后出现急性胸痛。12 导联心电图显示下肢体导联 ST 段抬高合并窦性停搏。立即给予舌下硝酸酯类药物，迅速缓解症状，同时心电图异常恢复正常。冠状动脉造影显示正常冠状动脉，提示疾病具有一过性特征。在冠心病监护病房密切监测下，重新给予小剂量吡啶斯的明，再次诱发胸痛。改用免疫抑制剂和长效硝酸酯类药物后，患者未再出现胸痛，MG 症状也得到良好控制。