From the Department of Gynecological Oncology Surgery (Ozgen), Faculty of Medicine, Uludag University, and from the Department of Obstetrics and Gynecology (Ozgen, Simsek, Dıncgez, Bayram, Mıdıkhan), Bursa Yuksek Ihtisas Training and Research Hospital, University of Health Sciences, Bursa, Turkey.
Saudi Med J. 2022 Sep;43(9):1046-1050. doi: 10.15537/smj.2022.43.9.20220291.
To examine the effects of early pregnancy loss on emotions such as depression, grief, or a sense of hopelessness, while investigating different types of diagnoses, hospital stays, and treatments.
A prospective cohort epidemiological study was carried out in Bursa Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey, between January and September 2019. The study included women diagnosed with early pregnancy loss classified into 3 groups: missed abortus, anembryonic pregnancy, and spontaneous abortion. The patients were screened via the Spielberger state-anxiety inventory (STAI-1) before initiating treatment. The Edinburgh postpartum depression scale (EPDS) and Perinatal Grief Scale (PGS) were also carried out in the first week of their hospital discharge.
The study was carried out with a total of 116 patients. The median gestational week of the patients was calculated at 9, their median hospital stay was 2 days, and their median dose of misoprostol was 800 mcg. The STAI-1 revealed that median values computed for women in all groups indicated moderate anxiety. The EDPS also demonstrated depression-positive median values for women in all 3 groups (EPDS>13). However, no statistically significant difference was noted in comparisons of the 3 groups apropos STAI-1, EPDS, and PGS.
Moderate anxiety, depressed mood, and perinatal grief were found in women diagnosed with early pregnancy loss, regardless of the type of abortion.
探讨不同类型的诊断、住院和治疗对早期妊娠丢失后抑郁、悲伤或绝望感等情绪的影响。
本前瞻性队列流行病学研究于 2019 年 1 月至 9 月在土耳其布尔萨 Yuksek Ihtisas 培训和研究医院进行。研究纳入了被诊断为早期妊娠丢失的女性，分为 3 组：难免流产、胚胎停育和自然流产。在开始治疗前，通过 Spielberger 状态焦虑量表（STAI-1）对患者进行筛查。在出院后的第一周，还进行了爱丁堡产后抑郁量表（EPDS）和围产期悲伤量表（PGS）的评估。
本研究共纳入了 116 例患者。患者的中位妊娠周数为 9 周，中位住院时间为 2 天，米索前列醇的中位剂量为 800 mcg。STAI-1 显示所有组别的女性中位数均提示存在中度焦虑。EPDS 也显示所有 3 组的女性均存在抑郁阳性的中位数（EPDS>13）。然而，3 组间在 STAI-1、EPDS 和 PGS 的比较中未观察到统计学显著差异。
无论流产类型如何，诊断为早期妊娠丢失的女性均存在中度焦虑、抑郁情绪和围产期悲伤。
