Safronova Elizaveta I, Galstyan Suzanna A, Kushel Yury V
Pediatric Neurosurgery Department, Burdenko Neurosurgical Center, 16, 4th Tverskaya-Yamskaya St, Moscow, Russia.
Pathology Department, Burdenko Neurosurgical Center, 16, 4th Tverskaya-Yamskaya St, Moscow, Russia.
Chin Neurosurg J. 2022 Sep 14;8(1):28. doi: 10.1186/s41016-022-00299-9.
Meningiomas are rather uncommon tumors in the pediatric population, differing significantly from those found in adults by their atypical location, higher rate of more malignant types, consequently higher risk of recurrence and a less favorable outcome. Even in children, suprasellar meningiomas without dural matrix are rare findings mimicking more common suprasellar lesions.
Here we describe a case of a 12-year-old girl who presented with a rapidly progressing chiasmal syndrome and was diagnosed by MRI with an unusual suprasellar tumor that could not fit the diagnoses expected in a case of a parasellar mass in a child, similar to a craniopharyngioma or optic pathway glioma. After multiple clinical investigations, the tumor etiology was still unclear, so the preferred option of treatment was surgical resection. An endoscope-assisted gross total resection through a supraorbital keyhole approach was performed uneventfully, with total vision recovery in a short time. Benign meningiomas located in the skull base without dural attachment appear to be rare, even in pediatric patients.
Differential diagnoses of suprasellar and para sellar tumor lesions in pediatric patients can be confusing. There are peculiar features of pediatric tumor diseases that should be considered while working out the management strategy. The main principle of meningioma treatment is the highest possible extent of resection minimally affecting the quality of life.
脑膜瘤在儿童群体中较为罕见,其非典型位置、更恶性类型的发生率较高、复发风险较高以及预后较差等方面与成人脑膜瘤有显著差异。即使在儿童中,无硬脑膜基质的鞍上脑膜瘤也是罕见的发现,易被误诊为更常见的鞍上病变。
在此,我们描述一例12岁女孩,她表现为快速进展的视交叉综合征,经磁共振成像(MRI)诊断为一种不寻常的鞍上肿瘤,该肿瘤不符合儿童鞍旁肿块(如颅咽管瘤或视路胶质瘤)的预期诊断。经过多次临床检查,肿瘤病因仍不明确,因此首选的治疗方案是手术切除。通过眶上锁孔入路在内镜辅助下顺利进行了肿瘤全切,患者视力在短时间内完全恢复。位于颅底且无硬脑膜附着的良性脑膜瘤似乎很罕见,即使在儿科患者中也是如此。
儿科患者鞍上和鞍旁肿瘤病变的鉴别诊断可能会令人困惑。在制定治疗策略时,应考虑儿科肿瘤疾病的特殊特征。脑膜瘤治疗的主要原则是在对生活质量影响最小的情况下尽可能进行最大范围的切除。