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经眉弓上眶内镜辅助锁孔入路治疗小儿鞍上脑膜瘤:病例报告及文献复习

Trans-eyebrow supraorbital endoscope-assisted keyhole approach to suprasellar meningioma in pediatric patient: case report and literature review.

作者信息

Safronova Elizaveta I, Galstyan Suzanna A, Kushel Yury V

机构信息

Pediatric Neurosurgery Department, Burdenko Neurosurgical Center, 16, 4th Tverskaya-Yamskaya St, Moscow, Russia.

Pathology Department, Burdenko Neurosurgical Center, 16, 4th Tverskaya-Yamskaya St, Moscow, Russia.

出版信息

Chin Neurosurg J. 2022 Sep 14;8(1):28. doi: 10.1186/s41016-022-00299-9.

DOI:10.1186/s41016-022-00299-9
PMID:36104809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9472336/
Abstract

BACKGROUND

Meningiomas are rather uncommon tumors in the pediatric population, differing significantly from those found in adults by their atypical location, higher rate of more malignant types, consequently higher risk of recurrence and a less favorable outcome. Even in children, suprasellar meningiomas without dural matrix are rare findings mimicking more common suprasellar lesions.

CASE PRESENTATION

Here we describe a case of a 12-year-old girl who presented with a rapidly progressing chiasmal syndrome and was diagnosed by MRI with an unusual suprasellar tumor that could not fit the diagnoses expected in a case of a parasellar mass in a child, similar to a craniopharyngioma or optic pathway glioma. After multiple clinical investigations, the tumor etiology was still unclear, so the preferred option of treatment was surgical resection. An endoscope-assisted gross total resection through a supraorbital keyhole approach was performed uneventfully, with total vision recovery in a short time. Benign meningiomas located in the skull base without dural attachment appear to be rare, even in pediatric patients.

CONCLUSION

Differential diagnoses of suprasellar and para sellar tumor lesions in pediatric patients can be confusing. There are peculiar features of pediatric tumor diseases that should be considered while working out the management strategy. The main principle of meningioma treatment is the highest possible extent of resection minimally affecting the quality of life.

摘要

背景

脑膜瘤在儿童群体中较为罕见,其非典型位置、更恶性类型的发生率较高、复发风险较高以及预后较差等方面与成人脑膜瘤有显著差异。即使在儿童中,无硬脑膜基质的鞍上脑膜瘤也是罕见的发现,易被误诊为更常见的鞍上病变。

病例报告

在此,我们描述一例12岁女孩,她表现为快速进展的视交叉综合征,经磁共振成像(MRI)诊断为一种不寻常的鞍上肿瘤,该肿瘤不符合儿童鞍旁肿块(如颅咽管瘤或视路胶质瘤)的预期诊断。经过多次临床检查,肿瘤病因仍不明确,因此首选的治疗方案是手术切除。通过眶上锁孔入路在内镜辅助下顺利进行了肿瘤全切,患者视力在短时间内完全恢复。位于颅底且无硬脑膜附着的良性脑膜瘤似乎很罕见,即使在儿科患者中也是如此。

结论

儿科患者鞍上和鞍旁肿瘤病变的鉴别诊断可能会令人困惑。在制定治疗策略时,应考虑儿科肿瘤疾病的特殊特征。脑膜瘤治疗的主要原则是在对生活质量影响最小的情况下尽可能进行最大范围的切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/a5bc65010ba0/41016_2022_299_Fig6_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/a5bc65010ba0/41016_2022_299_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/ab780d803381/41016_2022_299_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/e170eb208fe1/41016_2022_299_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/3bef58849ad8/41016_2022_299_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/271632fdc427/41016_2022_299_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/8d16ede0d27b/41016_2022_299_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/42ee/9472336/a5bc65010ba0/41016_2022_299_Fig6_HTML.jpg

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本文引用的文献

1
The epidemiology of primary and metastatic brain tumors in infancy through childhood.婴儿期至儿童期原发性和转移性脑肿瘤的流行病学。
J Neurooncol. 2022 Jan;156(2):419-429. doi: 10.1007/s11060-021-03927-z. Epub 2022 Jan 17.
2
Pediatric Skull Base Tumors: A Management Challenge.小儿颅底肿瘤:管理挑战
J Pediatr Neurosci. 2021 Jan-Mar;16(1):35-43. doi: 10.4103/jpn.JPN_56_20. Epub 2021 Jun 25.
3
Clinical features and long-term outcomes of pediatric meningiomas.儿童脑膜瘤的临床特征和长期预后。
Childs Nerv Syst. 2021 Oct;37(10):3041-3047. doi: 10.1007/s00381-021-05296-4. Epub 2021 Jul 22.
4
Meningioma: A Review of Epidemiology, Pathology, Diagnosis, Treatment, and Future Directions.脑膜瘤:流行病学、病理学、诊断、治疗及未来方向综述
Biomedicines. 2021 Mar 21;9(3):319. doi: 10.3390/biomedicines9030319.
5
Meningioma: A Review of Clinicopathological and Molecular Aspects.脑膜瘤:临床病理及分子学方面综述
Front Oncol. 2020 Oct 23;10:579599. doi: 10.3389/fonc.2020.579599. eCollection 2020.
6
Midline Meningiomas of the Anterior Skull Base: Surgical Outcomes and a Decision-Making Algorithm for Classic Skull Base Approaches.前颅底中线脑膜瘤:手术结果及经典颅底入路的决策算法
Cancers (Basel). 2020 Nov 3;12(11):3243. doi: 10.3390/cancers12113243.
7
Pediatric meningiomas: 10-year experience with 39 patients.小儿脑膜瘤:39 例患者 10 年经验。
J Neurooncol. 2020 Sep;149(3):543-553. doi: 10.1007/s11060-020-03649-8. Epub 2020 Oct 16.
8
The endoscope-assisted supraorbital "keyhole" approach for anterior skull base meningiomas: an updated meta-analysis.内镜辅助眶上锁孔入路治疗前颅底脑膜瘤:一项更新的荟萃分析。
Acta Neurochir (Wien). 2021 Mar;163(3):661-676. doi: 10.1007/s00701-020-04544-x. Epub 2020 Sep 5.
9
Comprehensive analysis of meningioma in the first two decades of life: A systematic review.20岁前脑膜瘤的综合分析:一项系统综述。
Neurochirurgie. 2020 Feb;66(1):36-40. doi: 10.1016/j.neuchi.2019.10.007. Epub 2019 Dec 3.
10
Long-Term Outcomes of Pediatric Meningioma Surgery: Single Center Experience with 23 Patients.儿童脑膜瘤手术的长期预后:23例患者的单中心经验
Turk Neurosurg. 2020;30(1):124-133. doi: 10.5137/1019-5149.JTN.27995-19.2.