Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Republic of Korea.
Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Medicine (Baltimore). 2022 Sep 2;101(35):e30077. doi: 10.1097/MD.0000000000030077.
A considerable number of Asian patients with functional dyspepsia (FD) are searching for complementary and alternative medicine (CAM) because they are unsatisfied with conventional medical treatment. However, no article has focused on CAM for FD from Asian perspective. In Asian countries, many traditional herbal formulas, including Banha-sasim-tang, Soyo-san, Sihosogan-san, Yukgunja-tang, and Pyeongwi-san, are used in patients with FD. In the few blinded and placebo-controlled studies conducted, the weak evidence regarding the effectiveness of herbal prescriptions in patients with FD did not allow any conclusions to be made. The clinical efficacy and safety of STW-5 were proven in several prospective randomized controlled trials and systematic reviews. Hence, it was recently approved as a therapeutic option for the treatment of FD. Peppermint and caraway, FDgard, black seed oil, and Jollab have been used in patients with FD, but there is limited evidence supporting their use. Reviews of acupuncture in patients with FD showed inconsistent results: a Cochrane review reported a negative result, while other meta-analyses reported positive results. Psychotherapy, including hypnotherapy, psychoanalytic psychotherapy, and cognitive behavioral therapy, may be used in patients with FD, although it is only supported by weak evidence. Therefore, well-planned, large-scale studies are necessary to evaluate the efficacy of CAM in treating FD, especially in Asian countries.
相当数量的功能性消化不良（FD）亚洲患者因对常规治疗不满意而寻求补充和替代医学（CAM）。然而，目前尚无从亚洲视角关注 FD 的 CAM 的文章。在亚洲国家，许多传统草药配方，包括半夏泻心汤、芍药甘草汤、四逆散、越鞠丸和平胃散，都用于 FD 患者。在进行的少数双盲和安慰剂对照研究中，关于草药处方在 FD 患者中的有效性的弱证据不允许得出任何结论。STW-5 的临床疗效和安全性已在几项前瞻性随机对照试验和系统评价中得到证实。因此，它最近被批准为治疗 FD 的治疗选择。薄荷和葛缕子、FDgard、黑种草油和 Jollab 已用于 FD 患者，但支持其使用的证据有限。对 FD 患者进行的针灸综述显示出不一致的结果：Cochrane 综述报告了阴性结果，而其他荟萃分析报告了阳性结果。心理治疗，包括催眠疗法、精神分析心理疗法和认知行为疗法，可用于 FD 患者，尽管仅得到弱证据的支持。因此，需要进行精心设计、大规模的研究来评估 CAM 治疗 FD 的疗效，特别是在亚洲国家。
