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功能性消化不良的补充和替代医学:亚洲视角。

Complementary and alternative medicine for functional dyspepsia: An Asian perspective.

机构信息

Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Republic of Korea.

Department of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.

出版信息

Medicine (Baltimore). 2022 Sep 2;101(35):e30077. doi: 10.1097/MD.0000000000030077.


DOI:10.1097/MD.0000000000030077
PMID:36107498
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9439791/
Abstract

A considerable number of Asian patients with functional dyspepsia (FD) are searching for complementary and alternative medicine (CAM) because they are unsatisfied with conventional medical treatment. However, no article has focused on CAM for FD from Asian perspective. In Asian countries, many traditional herbal formulas, including Banha-sasim-tang, Soyo-san, Sihosogan-san, Yukgunja-tang, and Pyeongwi-san, are used in patients with FD. In the few blinded and placebo-controlled studies conducted, the weak evidence regarding the effectiveness of herbal prescriptions in patients with FD did not allow any conclusions to be made. The clinical efficacy and safety of STW-5 were proven in several prospective randomized controlled trials and systematic reviews. Hence, it was recently approved as a therapeutic option for the treatment of FD. Peppermint and caraway, FDgard, black seed oil, and Jollab have been used in patients with FD, but there is limited evidence supporting their use. Reviews of acupuncture in patients with FD showed inconsistent results: a Cochrane review reported a negative result, while other meta-analyses reported positive results. Psychotherapy, including hypnotherapy, psychoanalytic psychotherapy, and cognitive behavioral therapy, may be used in patients with FD, although it is only supported by weak evidence. Therefore, well-planned, large-scale studies are necessary to evaluate the efficacy of CAM in treating FD, especially in Asian countries.

摘要

相当数量的功能性消化不良(FD)亚洲患者因对常规治疗不满意而寻求补充和替代医学(CAM)。然而,目前尚无从亚洲视角关注 FD 的 CAM 的文章。在亚洲国家,许多传统草药配方,包括半夏泻心汤、芍药甘草汤、四逆散、越鞠丸和平胃散,都用于 FD 患者。在进行的少数双盲和安慰剂对照研究中,关于草药处方在 FD 患者中的有效性的弱证据不允许得出任何结论。STW-5 的临床疗效和安全性已在几项前瞻性随机对照试验和系统评价中得到证实。因此,它最近被批准为治疗 FD 的治疗选择。薄荷和葛缕子、FDgard、黑种草油和 Jollab 已用于 FD 患者,但支持其使用的证据有限。对 FD 患者进行的针灸综述显示出不一致的结果:Cochrane 综述报告了阴性结果,而其他荟萃分析报告了阳性结果。心理治疗,包括催眠疗法、精神分析心理疗法和认知行为疗法,可用于 FD 患者,尽管仅得到弱证据的支持。因此,需要进行精心设计、大规模的研究来评估 CAM 治疗 FD 的疗效,特别是在亚洲国家。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9359/9439791/03c92b101efe/medi-101-e30077-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9359/9439791/7619202ae73f/medi-101-e30077-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9359/9439791/03c92b101efe/medi-101-e30077-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9359/9439791/7619202ae73f/medi-101-e30077-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9359/9439791/03c92b101efe/medi-101-e30077-g002.jpg

相似文献

[1]
Complementary and alternative medicine for functional dyspepsia: An Asian perspective.

Medicine (Baltimore). 2022-9-2

[2]
Banha-sasim-tang as an herbal formula for the treatment of functional dyspepsia: a randomized, double-blind, placebo-controlled, two-center trial.

Trials. 2010-7-30

[3]
Herbal medicine Banha-sasim-tang for the treatment of functional dyspepsia protocol for a systematic review of randomized controlled trials.

Medicine (Baltimore). 2019-5

[4]
Herbal Medicine Yukgunja-Tang for Functional Dyspepsia: A Protocol for a Randomized, Controlled, Multicenter Clinical Trial.

Healthcare (Basel). 2023-5-17

[5]
Herbal medicine Yukgunja-tang for functional dyspepsia protocol for a systematic review of randomized controlled trials.

Medicine (Baltimore). 2018-10

[6]
A traditional herbal formula, Hyangsa-Pyeongwi san (HPS), improves quality of life (QoL) of the patient with functional dyspepsia (FD): randomized double-blinded controlled trial.

J Ethnopharmacol. 2013-11-13

[7]
Efficacy of Banha-sasim-tang on functional dyspepsia classified as excess pattern: study protocol for a randomized controlled trial.

Trials. 2017-11-9

[8]
Herbal medicine Siho-sogan-san for functional dyspepsia: A protocol for a systematic review and meta-analysis.

Medicine (Baltimore). 2020-9-25

[9]
Safety and efficacy of Soyo-san for the treatment of functional dyspepsia: A protocol for systematic review and meta-analysis.

Medicine (Baltimore). 2020-9-25

[10]
Efficacy and safety of jollab to treat functional dyspepsia: a randomized placebo-controlled clinical trial.

Explore (NY). 2015

引用本文的文献

[1]
Case Report: Improvement of functional dyspepsia using eight constitution acupuncture and eight constitution diet - A report of three cases.

Front Med (Lausanne). 2025-7-23

[2]
The effect of therapeutic massage combined with conventional therapy in children with functional dyspepsia: a systematic review and meta-analysis.

Front Pharmacol. 2025-4-16

[3]
, a standardized herbal formula, promotes gastrointestinal motility via modulation of the acetylcholine pathway in a loperamide-induced functional dyspepsia mice.

Pharm Biol. 2025-12

[4]
Food, Dietary Patterns, or Is Eating Behavior to Blame? Analyzing the Nutritional Aspects of Functional Dyspepsia.

Nutrients. 2023-3-22

[5]
Research trends in the field of the gut-brain interaction: Functional dyspepsia in the spotlight - An integrated bibliometric and science mapping approach.

Front Neurosci. 2023-3-8

本文引用的文献

[1]
Herbal medicine Siho-sogan-san for functional dyspepsia: A protocol for a systematic review and meta-analysis.

Medicine (Baltimore). 2020-9-25

[2]
Effects of the herbal medicine Rikkunshito, for functional dyspepsia: A systematic review and meta-analysis.

J Gastroenterol Hepatol. 2021-1

[3]
Complementary and Alternative Medicine for Functional Gastrointestinal Disorders.

Am J Gastroenterol. 2020-3

[4]
A Combination of Peppermint Oil and Caraway Oil for the Treatment of Functional Dyspepsia: A Systematic Review and Meta-Analysis.

Evid Based Complement Alternat Med. 2019-11-14

[5]
Herbal medicine in the treatment of functional gastrointestinal disorders: A systematic review with meta-analysis.

J Gastroenterol Hepatol. 2019-11-7

[6]
The Efficacy of Hypnotherapy in the Treatment of Functional Dyspepsia.

Am J Ther. 2019

[7]
Herbal medicine Banha-sasim-tang for the treatment of functional dyspepsia protocol for a systematic review of randomized controlled trials.

Medicine (Baltimore). 2019-5

[8]
A Novel, Duodenal-Release Formulation of a Combination of Caraway Oil and L-Menthol for the Treatment of Functional Dyspepsia: A Randomized Controlled Trial.

Clin Transl Gastroenterol. 2019-4

[9]
Gut-focused hypnotherapy for Functional Gastrointestinal Disorders: Evidence-base, practical aspects, and the Manchester Protocol.

Neurogastroenterol Motil. 2019-2-27

[10]
The prevalence and characteristics of complementary medicine use by Australian and American adults living with gastrointestinal disorders: A systematic review.

Complement Ther Med. 2018-9-4

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