Clinkenbeard K D, Cowell R L, Tyler R D
J Am Vet Med Assoc. 1987 Jun 1;190(11):1445-8.
Anemia, weight loss, lethargy, fever, anorexia, and interstitial lung disease were the predominant clinical findings in 12 cats with disseminated histoplasmosis. Some cats were examined because of dysfunction or lesions of bone, eyes, or skin. In most cases, the clinical signs were observed by the owner for 4 weeks or less before seeking veterinary care. Young cats were most commonly affected, with 7 of the 12 cats less than or equal to 1 year old. Identification of Histoplasma organisms in bone marrow aspirates was used to confirm the diagnosis of histoplasmosis in 11 of the 12 cats. Histoplasma infection of multiple organs was found at necropsy. In this study, disseminated histoplasmosis had a higher prevalence in cats than in dogs at the same veterinary medical teaching hospital. Feline disseminated histoplasmosis was not associated with FeLV infection. Treatment was attempted in 7 of the 12 cats.
贫血、体重减轻、嗜睡、发热、厌食和间质性肺病是12只播散性组织胞浆菌病猫的主要临床症状。一些猫因骨骼、眼睛或皮肤功能障碍或病变而接受检查。在大多数情况下，主人在寻求兽医治疗前观察到临床症状的时间为4周或更短。幼猫最常受到影响，12只猫中有7只小于或等于1岁。通过骨髓穿刺物中组织胞浆菌的鉴定，12只猫中有11只确诊为组织胞浆菌病。尸检发现多个器官存在组织胞浆菌感染。在同一兽医学院教学医院，本研究中猫播散性组织胞浆菌病的患病率高于犬。猫播散性组织胞浆菌病与猫白血病病毒（FeLV）感染无关。12只猫中有7只尝试进行了治疗。
