Singhania Ashika, Sathe Seema, Ranka Rajul, Godbole Surekha
Prosthodontics, Sharad Pawar Dental College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Cardiovascular Medicine, Houston Methodist Hospital, Houston, USA.
Cureus. 2022 Aug 10;14(8):e27869. doi: 10.7759/cureus.27869. eCollection 2022 Aug.
Background Inflammation is present in denture stomatitis. Denture stomatitis's etiology is complex, but there is evidence that it is brought on by growing in biofilms on its surface. Objective This study aimed to examine and assess the effectiveness of several herbal products, such as tea tree oil and neem extracts, on adhesion to denture soft liners. Method Each wall of the tissue culture plate was filled with 30 acrylic blocks lined with soft liners, followed by the addition of 0.1 ml of the standardized suspension, which was then left to incubate for 48 hours. Each specimen was placed in a disinfectant solution for 10 minutes. A colony was counted after 0.1ml of the solution was plated on a sabouraud dextrose agar (SDA) plate and cultured for 72 hours. Data were compared using a one-way analysis of variance (ANOVA) test. Results The mean colony forming units (CFU) per ml for combined tea tree oil and neem extract was least (0.40), followed by tea tree oil (2.30), followed by neem extract (30.33). The treated blocks were effective in reducing the growth of . Conclusion Combining tea tree oil and neem extract significantly reduced the growth of suggesting a new form of intraoral effective antifungal treatment.
义齿性口炎存在炎症。义齿性口炎的病因复杂，但有证据表明它是由其表面生物膜生长引起的。目的：本研究旨在检测和评估几种草药产品，如茶树油和印楝提取物，对义齿软衬材料黏附的有效性。方法：在组织培养板的每个孔壁中填充30个衬有软衬材料的丙烯酸块，然后加入0.1ml标准化悬浮液，接着孵育48小时。每个标本置于消毒溶液中10分钟。将0.1ml溶液接种于沙氏葡萄糖琼脂（SDA）平板上培养72小时后进行菌落计数。使用单因素方差分析（ANOVA）检验比较数据。结果：每毫升中茶树油和印楝提取物组合的平均菌落形成单位（CFU）最少（0.40），其次是茶树油（2.30），然后是印楝提取物（30.33）。经处理的块在减少……生长方面有效。结论：茶树油和印楝提取物组合显著减少了……的生长，提示一种新的口腔内有效抗真菌治疗形式。
