Gibler Robert C, Knestrick Kaelynn E, Reidy Brooke L, Lax Daniel N, Powers Scott W
Division of Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Pediatric Health Med Ther. 2022 Sep 9;13:309-323. doi: 10.2147/PHMT.S334744. eCollection 2022.
Migraine is a neurological disorder that affects millions of children and adolescents worldwide. Chronic migraine is a subtype of migraine in which patients experience headaches for more days than not each month, with accompanying symptoms of phonophobia, photophobia, nausea or vomiting for most of these headaches. The burden and impact of chronic migraine in the daily lives of children and adolescents is substantial, requiring a holistic, multidisciplinary, and biopsychosocial approach to conceptualization and treatment. The purpose of this review is to provide a comprehensive "2022" overview of acute and preventive treatments for the management of chronic migraine in youth. We first describe diagnostic criteria for chronic migraine and highlight the state of evidence for acute and preventive treatment in children and adolescents. We then discuss emerging treatments currently receiving rigorous clinical research effort, special considerations for the treatment of chronic migraine in children and adolescents, and avenues for improving existing treatments and expanding access to evidence-based care.
偏头痛是一种影响全球数百万儿童和青少年的神经系统疾病。慢性偏头痛是偏头痛的一种亚型,患者每月头痛天数超过半数,且大多数头痛伴有恐声症、畏光症、恶心或呕吐等症状。慢性偏头痛对儿童和青少年日常生活的负担和影响很大,需要采用整体、多学科和生物心理社会方法进行概念化和治疗。本综述的目的是全面概述2022年用于治疗青少年慢性偏头痛的急性和预防性治疗方法。我们首先描述慢性偏头痛的诊断标准,并强调儿童和青少年急性和预防性治疗的证据状况。然后,我们讨论目前正在接受严格临床研究的新兴治疗方法、儿童和青少年慢性偏头痛治疗的特殊考虑因素,以及改进现有治疗方法和扩大循证护理可及性的途径。