Netrin-1、DCC、UNC5B 和 VEGF 在稽留流产患者绒毛组织中的表达及相关性研究。
Expression and Relationship of Netrin-1, DCC, UNC5B, and VEGF in Villous Tissues of Patients with Delayed Abortion.
机构信息
Huai'an Maternal and Child Health Care Center, Huai'an 223001, China.
Department of Breast Thyroid and Vascular Surgery, The Affiliated Huai'an Hospital of Xuzhou Medical University and the Second People's Hospital of Huai'an, Huai'an 223001, China.
出版信息
Contrast Media Mol Imaging. 2022 Aug 30;2022:6283372. doi: 10.1155/2022/6283372. eCollection 2022.
In order to investigate the correlation between neuroaxon-guiding factor (Netrin-1), deleted in colorectal cancer (DCC), uncoordinated 5B (UNC5B), and vascular endothelial growth factor (VEGF) expression machine in villus tissues of delayed abortion in colorectal cancer, a total of 120 pregnant women are selected from February 2019 to August 2021. The two groups of subjects improve the relevant examinations before surgery and the underwent negative pressure induces abortion hysterectomy guided by abdominal ultrasound under intravenous anesthesia. The mRNA and protein expressions of netrin-1, DCC, UNC5B, and VEGF in the villi of the two groups are detected by real-time fluorescence quantitative polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC), and the correlation of the four indicators is analyzed by Pearson's test.
为了研究神经轴突导向因子（Netrin-1）、结直肠癌缺失基因（DCC）、未协调蛋白 5B（UNC5B）和血管内皮生长因子（VEGF）在结直肠癌延迟流产绒毛组织中的表达关系，选择了 2019 年 2 月至 2021 年 8 月间的 120 名孕妇。两组患者均在术前进行相关检查，然后在静脉麻醉下通过腹部超声引导负压诱导流产子宫切除术。采用实时荧光定量聚合酶链反应（RT-PCR）和免疫组织化学（IHC）检测两组绒毛中 netrin-1、DCC、UNC5B 和 VEGF 的 mRNA 和蛋白表达，并通过 Pearson 检验分析这四个指标之间的相关性。
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