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使用脂肪补片进行硬脑膜修复治疗特发性脊髓疝:手术技术及7例病例回顾

Dural repair with fat patch for idiopathic spinal cord herniation: operative technique and a review of seven cases.

作者信息

Zhang Lei, Wu Hao, Liu Zhenlei, Wang Xingwen, Cheng Ye, Wang Kai

机构信息

Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Spine Center, China International Neuroscience Institute (CHINA-INI), Beijing, China.

出版信息

Ann Transl Med. 2022 Aug;10(16):865. doi: 10.21037/atm-22-3343.

Abstract

BACKGROUND

Idiopathic ventral thoracic spinal cord herniation is a rare disease presented with progressive myelopathy or Brown Séquard syndrome, causing neurological deficits. There is no consensus on etiology and surgical strategy. The purpose of the present study is to report the case series using fat patch for the repair of the ventral dural defect with clinical follow up.

METHODS

A retrospective review of all cases of idiopathic spinal cord herniation (ISCH) at our institution was performed between January 2017 and June 2021. Clinical data were reviewed including patients' demographic information, symptoms, imaging, operative details, perioperative and postoperative courses, and clinical outcomes, and complications. Japanese Orthopedic Association (JOA) score was calculated preoperatively and postoperatively for the comparison of outcomes.

RESULTS

A total of 7 patients were included. Fat patch was applied in all cases, and artificial dural patch was also used in 2 cases. Average operating time and estimated blood loss were 3 hours and 24 minutes and 88.6 mL, respectively. Five of 7 patients improved and 2 patients remained unchanged during follow up (average, 23.4 months; range, 9-42 months). The mean recovery rate (RR) of JOA score was 17.9%. One patient experienced cerebrospinal fluid (CSF) leakage, and 1 patient suffered from surgical related spinal canal stenosis.

CONCLUSIONS

Surgical treatment using fat patch is an effective strategy for the ventral dural defect repair of ISCH.

摘要

背景

特发性胸段脊髓腹侧疝是一种罕见疾病,表现为进行性脊髓病或布朗 - 塞卡尔综合征,导致神经功能缺损。目前对于其病因和手术策略尚无共识。本研究的目的是报告一系列使用脂肪补片修复腹侧硬脊膜缺损并进行临床随访的病例。

方法

对2017年1月至2021年6月在本机构就诊的所有特发性脊髓疝(ISCH)病例进行回顾性分析。回顾临床资料,包括患者的人口统计学信息、症状、影像学检查、手术细节、围手术期和术后病程、临床结局及并发症。术前和术后计算日本骨科协会(JOA)评分以比较治疗效果。

结果

共纳入7例患者。所有病例均应用了脂肪补片,2例还使用了人工硬脊膜补片。平均手术时间为3小时24分钟,平均估计失血量为88.6毫升。7例患者中有5例在随访期间病情改善,2例无变化(平均随访时间23.4个月;范围9 - 42个月)。JOA评分的平均恢复率(RR)为17.9%。1例患者出现脑脊液漏,1例患者发生与手术相关的椎管狭窄。

结论

使用脂肪补片进行手术治疗是修复ISCH腹侧硬脊膜缺损的有效策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6abf/9469156/419b56c2b5f2/atm-10-16-865-f1.jpg

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