Areekal Sandra Aravind, Goel Pranay, Khadilkar Anuradha, Khadilkar Vaman, Cole Tim J
Department of Biology, Indian Institute of Science Education and Research, Pune, India.
Hirabai Cowasji Jehangir Medical Research Institute, Pune, India.
Ann Hum Biol. 2022 Sep;49(5-6):228-235. doi: 10.1080/03014460.2022.2107238.
Growth centiles and growth curves are two ways to present child anthropometry; however, they differ in the type of data used, the method of analysis, the biological parameters fitted and the form of interpretation.
To fit and compare height growth centiles and curves in Indian children.
1468 children (796 boys) from Pune India aged 6-18 years with longitudinal data on age and height (n = 7781) were analysed using GAMLSS (Generalised Additive Models for Location Scale and Shape) for growth centiles, and SITAR (SuperImposition by Rotation and Translation) for growth curves.
SITAR explained 98.7% and 98.8% of the height variance in boys and girls, with mean age at peak height velocity 13.1 and 11.0 years, and mean peak velocity 9.0 and 8.0 cm/year, respectively. GAMLSS (Box-Cox Cole Green model) also captured the pubertal growth spurt but the centiles were shallower than the SITAR mean curve. Boys showed a mid-growth spurt at age 8 years.
GAMLSS displays the distribution of height in the population by age and sex, while SITAR effectively and parsimoniously summarises the pattern of height growth in individual children. The two approaches provide distinct, useful information about child growth.
生长百分位数和生长曲线是呈现儿童人体测量数据的两种方式；然而，它们在所用数据类型、分析方法、拟合的生物学参数以及解释形式上存在差异。
拟合并比较印度儿童的身高生长百分位数和生长曲线。
对来自印度浦那的1468名6至18岁儿童（796名男孩）进行分析，这些儿童有年龄和身高的纵向数据（n = 7781），使用广义相加模型定位尺度和形状（GAMLSS）来计算生长百分位数，使用旋转和平移叠加法（SITAR）来绘制生长曲线。
SITAR解释了男孩和女孩身高变异的98.7%和98.8%，身高增长峰值速度的平均年龄分别为13.1岁和11.0岁，平均峰值速度分别为9.0厘米/年和8.0厘米/年。GAMLSS（Box-Cox Cole Green模型）也捕捉到了青春期生长突增，但百分位数比SITAR平均曲线更平缓。男孩在8岁时出现中期生长突增。
GAMLSS按年龄和性别展示了人群中的身高分布，而SITAR有效且简洁地总结了个体儿童的身高增长模式。这两种方法提供了关于儿童生长的不同但有用的信息。
