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剖宫产术后手术部位感染的术前和术后全血细胞计数及预测:一项回顾性病例对照研究

Preoperative and postoperative complete blood cell counts and prediction of surgical site infection after cesarean delivery: a retrospective case-control study.

作者信息

Aktoz Fatih, Tercan Can, Cigdem Busra, Vurgun Eren

机构信息

Department of Obstetrics and Gynecology, Basaksehir Cam and Sakura City Hospital, Istanbul, Turkey.

Department of Medical Biochemistry, Prof. Dr. Cemil Tascioglu City Hospital, Istanbul, Turkey.

出版信息

Wound Manag Prev. 2022 Sep;68(9):19-23.

Abstract

BACKGROUND

Cesarean delivery (CD) is the most frequently performed surgery. Surgical site infection (SSI) is a common complication after CD.

PURPOSE

To evaluate the role of complete blood count parameters in predicting the development of SSI after CD.

METHODS

Patients who were hospitalized because of SSI after CD were included in the SSI group (n = 48). A control group (n = 45) was formed with healthy postpartum women who had also undergone CD. Preoperative and postoperative hemoglobin (Hb), white blood cell count (WBC), neutrophil count, lymphocyte count, platelet count (PLT), neutrophil-to-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), mean platelet volume (MPV), and platelet-large cell ratio (P-LCR) were recorded.

RESULTS

WBC, neutrophil count, and NLR levels increased while Hb, PLT, and lymphocyte count levels decreased after CD in both the SSI and control groups. PLR increased after CD in the SSI group but remained stable in the control group. However, the difference in PLR could not predict SSI after CD.

CONCLUSION

Complete blood count parameters were not useful to predict SSI after CD. Larger prospective studies are needed.

摘要

背景

剖宫产是最常施行的手术。手术部位感染是剖宫产术后的常见并发症。

目的

评估血常规参数在预测剖宫产术后手术部位感染发生中的作用。

方法

将因剖宫产术后手术部位感染而住院的患者纳入手术部位感染组(n = 48)。选取同样接受剖宫产的健康产后女性组成对照组(n = 45)。记录术前及术后的血红蛋白(Hb)、白细胞计数(WBC)、中性粒细胞计数、淋巴细胞计数、血小板计数(PLT)、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)、平均血小板体积(MPV)以及血小板大细胞比值(P-LCR)。

结果

手术部位感染组和对照组剖宫产术后白细胞、中性粒细胞计数及中性粒细胞与淋巴细胞比值水平均升高,而血红蛋白、血小板及淋巴细胞计数水平均降低。手术部位感染组剖宫产术后血小板与淋巴细胞比值升高,而对照组保持稳定。然而,血小板与淋巴细胞比值的差异无法预测剖宫产术后的手术部位感染。

结论

血常规参数对预测剖宫产术后手术部位感染并无作用。需要开展更大规模的前瞻性研究。

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