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输卵管卵巢脓肿手术患者术中并发症发生率及危险因素的确定:一项回顾性队列研究。

Determination of intraoperative complication rate and risk factors in patients undergoing surgery for tubo-ovarian abscess: A retrospective cohort study.

作者信息

Tas Emre Erdem

机构信息

Department of Obstetrics and Gynecology, Ankara Yildirim Beyazit University, Ankara, Turkey.

出版信息

Medicine (Baltimore). 2025 Feb 14;104(7):e41508. doi: 10.1097/MD.0000000000041508.

Abstract

This study aimed to assess intraoperative complication rates and risk factors in patients who underwent surgery for tubo-ovarian abscess. A retrospective review of the medical records of 170 patients who underwent tubo-ovarian abscess surgery between January 2014 and December 2023 was conducted. Four patients were excluded due to a histopathologic diagnosis of cancer, and 166 patients were included in the final analysis. Intraoperative complications were observed in 10 (6.0%) patients, including 8 (4.8%) and 2 (1.2%) patients with bowel and bladder injuries, respectively. The included patients were categorized into complication-positive (n = 10, 6.0%) and complication-negative (n = 156, 94.0%) groups, with between groups comparisons based on demographic, clinical, and surgical characteristics. The complication-positive group had significantly higher mean age and serum c-reactive protein (CRP) levels than the complication-negative group (46.6 ± 7.4 years vs 40.6 ± 8.5 years; P = .03, and 199.2 ± 89.4 mg/L vs 112.2 ± 84.2 mg/L; P ≤ .01, respectively). Extensive surgery, such as hysterectomy with bilateral adnexectomy, was more commonly performed in the complication-positive group than in the complication-negative group (8/10 [80.0%] vs 43/156 [27.5%], P < .01). Receiver operating characteristic curve analysis identified a serum CRP level of 186.5 mg/L as the optimal cutoff for predicting intraoperative complications. Binary logistic regression analysis showed that elevated serum CRP levels (≥186.5 mg/L) (odds ratio: 7.9; P < .01) and extensive surgery (odds ratio: 11.0, P = .01) were independently associated with intraoperative complications. Our findings indicate that elevated serum CRP levels and extensive surgery are associated with increased intraoperative complication risks, which may have important implications in clinical practice, potentially informing preoperative assessments, and surgical planning. This study was reported in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology statement.

摘要

本研究旨在评估接受输卵管卵巢脓肿手术患者的术中并发症发生率及危险因素。对2014年1月至2023年12月期间170例行输卵管卵巢脓肿手术患者的病历进行回顾性分析。4例因组织病理学诊断为癌症被排除,最终纳入166例患者进行分析。10例(6.0%)患者出现术中并发症,其中分别有8例(4.8%)和2例(1.2%)患者发生肠损伤和膀胱损伤。将纳入患者分为并发症阳性组(n = 10,6.0%)和并发症阴性组(n = 156,94.0%),并基于人口统计学、临床和手术特征进行组间比较。并发症阳性组的平均年龄和血清C反应蛋白(CRP)水平显著高于并发症阴性组(46.6 ± 7.4岁 vs 40.6 ± 8.5岁;P = 0.03,以及199.2 ± 89.4mg/L vs 112.2 ± 84.2mg/L;P≤0.01)。与并发症阴性组相比,并发症阳性组更常进行广泛手术,如子宫切除术加双侧附件切除术(8/10 [80.0%] vs 43/156 [27.5%],P < 0.01)。受试者工作特征曲线分析确定血清CRP水平186.5mg/L为预测术中并发症的最佳临界值。二元逻辑回归分析显示,血清CRP水平升高(≥186.5mg/L)(比值比:7.9;P < 0.01)和广泛手术(比值比:11.0,P = 0.01)与术中并发症独立相关。我们的研究结果表明,血清CRP水平升高和广泛手术与术中并发症风险增加相关,这在临床实践中可能具有重要意义,可能为术前评估和手术规划提供参考。本研究按照《加强流行病学观察性研究报告声明》进行报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e234/11835069/5d6f416bfa92/medi-104-e41508-g001.jpg

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