Brown M C
J Comp Neurol. 1987 Jun 22;260(4):605-18. doi: 10.1002/cne.902600412.
Efferent axons to the guinea pig cochlea were labeled by extracellular injections of horseradish peroxidase into the intraganglionic spiral bundle within the spiral ganglion. The terminal fibers formed by these axons were classified according to their patterns of termination within the basal turn of the cochlea. A class of terminal fibers designated "autonomic" forms a highly branched plexus in the osseous spiral lamina but does not enter the organ of Corti. The termination of single autonomics includes blood vessels as well as areas of the osseous spiral lamina not adjacent to blood vessels. Two major classes of efferent axons from the olivocochlear bundle enter the cochlea by way of the vestibulocochlear anastomosis and terminate either in areas near inner hair cells (IHC efferents) or onto outer hair cells (OHC efferents). The IHC efferents have thin axons throughout their course within the cochlea and can be divided into two subclasses. The most numerous subclass of IHC efferents (unidirectional) enters the inner spiral bundle and turns to spiral in only one direction for less than 1 mm and then forms a discrete termination including many en passant and terminal swellings that are within both the inner and tunnel spiral bundles. A less common subclass of IHC efferents (bidirectional) bifurcates upon entry into the inner spiral bundle to send branches both apically and basally. These terminal fibers take spiral courses that are greater than 1 mm in extent, often course in the tunnel spiral bundle for a large portion of the spiral, and form terminals throughout their extended spiral course. None of the IHC efferent fibers send branches to cross the tunnel to innervate the outer hair cells. A second major class of olivocochlear fibers, OHC efferent fibers, forms large boutons on the outer hair cells, and although they sometimes spiral beneath the IHCs for some length, they do not give off terminals to this region. The OHC efferent axons are thick and myelinated as they enter the cochlea, and they branch near the spiral ganglion to form several terminal fibers. Some of these terminal fibers are thin as they travel from the intraganglionic spiral bundle across the osseous spiral lamina to the organ of Corti, whereas others are thick and obviously myelinated as far peripheral as the habenula.(ABSTRACT TRUNCATED AT 400 WORDS)
通过将辣根过氧化物酶细胞外注射到螺旋神经节内的神经节内螺旋束中，标记了豚鼠耳蜗的传出轴突。由这些轴突形成的终末纤维根据其在耳蜗基部转弯处的终止模式进行分类。一类被称为“自主神经的”终末纤维在骨螺旋板中形成高度分支的丛，但不进入柯蒂氏器。单个自主神经纤维的终止部位包括血管以及骨螺旋板中不与血管相邻的区域。来自橄榄耳蜗束的两类主要传出轴突通过前庭耳蜗吻合进入耳蜗，并终止于内毛细胞附近区域（内毛细胞传出纤维）或外毛细胞上（外毛细胞传出纤维）。内毛细胞传出纤维在耳蜗内全程都有细轴突，可分为两个亚类。内毛细胞传出纤维中数量最多的亚类（单向的）进入内螺旋束，仅在一个方向上螺旋不到1毫米，然后形成离散的终末，包括许多串珠状和终末膨大，位于内螺旋束和隧道螺旋束内。内毛细胞传出纤维中较不常见的亚类（双向的）在进入内螺旋束时会分叉，向顶端和基部都发出分支。这些终末纤维的螺旋行程超过1毫米，在螺旋的大部分行程中通常走行于隧道螺旋束中，并在其延伸的螺旋行程中形成终末。没有内毛细胞传出纤维会发出分支穿过隧道去支配外毛细胞。第二类主要的橄榄耳蜗纤维，即外毛细胞传出纤维，在外毛细胞上形成大的终扣，尽管它们有时会在内毛细胞下方螺旋一段距离，但不会向该区域发出终末。外毛细胞传出轴突在进入耳蜗时是粗的且有髓鞘，它们在螺旋神经节附近分支形成几条终末纤维。其中一些终末纤维从神经节内螺旋束穿过骨螺旋板到柯蒂氏器的行程中是细的，而另一些则一直到缰孔都是粗的且明显有髓鞘。（摘要截断于400字）
