College of Arts and Sciences, Emory University, Atlanta, GA, USA.
School of Arts and Sciences, Tufts University, Medford, MA, USA.
Brain Imaging Behav. 2022 Dec;16(6):2785-2796. doi: 10.1007/s11682-022-00724-8. Epub 2022 Sep 17.
Diversity of participants in biomedical research with respect to race, ethnicity, and biological sex is crucial, particularly given differences in disease prevalence, recovery, and survival rates between demographic groups. The objective of this systematic review was to report on the demographics of neuroimaging studies using magnetic resonance imaging (MRI). The Web of Science database was used and data collection was performed between June 2021 to November 2021; all articles were reviewed independently by at least two researchers. Articles utilizing MR data acquired in the United States, with n ≥ 10 human subjects, and published between 2010-2020 were included. Non-primary research articles and those published in journals that did not meet a quality control check were excluded. Of the 408 studies meeting inclusion criteria, approximately 77% report sex, 10% report race, and 4% report ethnicity. Demographic reporting also varied as function of disease studied, participant age range, funding, and publisher. We anticipate quantitative data on the extent, or lack, of reporting will be necessary to ensure inclusion of diverse populations in biomedical research.
生物医学研究中参与者的多样性(如种族、民族和生物性别)至关重要,特别是考虑到不同人群之间疾病的发病率、康复率和存活率存在差异。本系统评价的目的是报告使用磁共振成像(MRI)的神经影像学研究的人口统计学特征。使用了 Web of Science 数据库,并于 2021 年 6 月至 2021 年 11 月期间进行了数据收集;至少有两名研究人员独立审查了所有文章。纳入了在美国使用 MR 数据、n≥10 名人类受试者且发表于 2010-2020 年期间的主要研究文章。排除了非主要研究文章和未通过质量控制检查的期刊发表的文章。在符合纳入标准的 408 项研究中,约 77%报告了性别,10%报告了种族,4%报告了民族。人口统计学报告也因所研究的疾病、参与者的年龄范围、资金和出版商而异。我们预计,关于报告的程度或缺乏程度的定量数据对于确保在生物医学研究中纳入不同人群是必要的。