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肤色还是金钱?社会经济地位和种族/民族对乳腺癌死亡率的影响

Color or money?: The impact of socioeconomic status and race/ethnicity on breast cancer mortality.

作者信息

Nnorom Siobhan O, Akinyemi Oluwasegun, Tran Joseph, Baig Hana, Cornwell Edward E, Frederick Wayne A, Wilson Lori L

机构信息

Clive O. Callender Health Sciences Outcomes Research Center, Howard University College of Medicine, 520 W St NW, Washington, DC, 20059, USA.

Clive O. Callender Health Sciences Outcomes Research Center, Howard University College of Medicine, 520 W St NW, Washington, DC, 20059, USA.

出版信息

Am J Surg. 2022 Dec;224(6):1403-1408. doi: 10.1016/j.amjsurg.2022.07.013. Epub 2022 Aug 24.

Abstract

BACKGROUND

Although the incidence of breast cancer is highest in White women, Black women die at a higher rate. Our aim was to compare the relative association between race/ethnicity and socioeconomic status on breast cancer mortality.

METHODS

We identified female breast cancer patients diagnosed between 2007 - 2011 and followed through 2016 in the SEER database. Patients were grouped into socioeconomic quartiles by a prosperity index. The primary outcome of interest was 5-year cancer-specific survival.

RESULTS

A total of 286,520 patients were included. Five-year survival was worst for Black women compared to other races/ethnicities in each socioeconomic quartile. When compared to White women in the lowest quartile, Black women in the lowest quartile, 2nd quartile, and 3rd quartile experienced the lowest 5-year survival rates (Hazard ratio 1.33, 1.23, 1.20; P < 0.01).

CONCLUSION

Regarding cancer mortality, only in the most prosperous quartile do Black women achieve a similar outcome to the poorest quartile White women.

摘要

背景

尽管白人女性乳腺癌发病率最高,但黑人女性死亡率更高。我们的目的是比较种族/民族与社会经济地位对乳腺癌死亡率的相对关联。

方法

我们在监测、流行病学和最终结果(SEER)数据库中确定了2007年至2011年期间确诊且随访至2016年的女性乳腺癌患者。患者按繁荣指数分为社会经济四分位数组。主要关注的结局是5年癌症特异性生存率。

结果

共纳入286,520例患者。在每个社会经济四分位数组中,黑人女性的5年生存率相比其他种族/民族最差。与最低四分位数组的白人女性相比,最低四分位数组、第二四分位数组和第三四分位数组的黑人女性5年生存率最低(风险比分别为1.33、1.23、1.20;P < 0.01)。

结论

关于癌症死亡率,只有在最富裕的四分位数组中,黑人女性的结局才与最贫穷四分位数组的白人女性相似。

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