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药师激励性访谈对糖尿病成人乙型肝炎疫苗接种的影响。

Impact of pharmacist motivational interviewing on hepatitis B vaccination in adults with diabetes.

出版信息

J Am Pharm Assoc (2003). 2023 Jan-Feb;63(1):66-73.e1. doi: 10.1016/j.japh.2022.08.013. Epub 2022 Aug 19.

Abstract

BACKGROUND

In 2011, the Advisory Committee on Immunization Practices recommended hepatitis B (HepB) vaccination for previously unvaccinated adults (aged 19-59 years) with diabetes. Despite these recommendations, vaccination coverage for HepB vaccination for persons with diabetes remains low.

OBJECTIVES

The primary objective was to determine the impact of a community pharmacist-led motivational interviewing (MI) intervention on HepB vaccination initiation among adults with diabetes who were previously unvaccinated against HepB. The secondary objective was to describe HepB vaccination series completion among adults with diabetes who initiated the first dose of a HepB vaccine.

METHODS

A prospective, nonrandomized, controlled cluster trial was conducted across 58 regional grocery store chain pharmacies: a total of 29 pharmacies in the MI group and 29 pharmacies in the control group. Pharmacy location-level baseline data were collected during a 12-month pre-program period. The MI program was delivered over 10 months. Alerts were generated during prescription processing throughout the study period for eligible patients at each MI pharmacy location. The MI consisted of a face-to-face conversation between the pharmacist and the patient at the time of prescription pick-up. The difference in the primary outcome of HepB vaccination series initiation between patients receiving MI and control patients was assessed using a difference-in-differences analysis. For series completion, patients who initiated the HepB vaccination series were followed up for over 12 months after their first HepB vaccine dose.

RESULTS

There was a statistically significant 3.711% increase in HepB vaccination when comparing eligible individuals who received the MI intervention (n = 1569) to eligible individuals in the control group (n = 3640). Of the patients in the MI group who initiated HepB vaccination, 40 of 65 patients (61.5%) completed the vaccination series.

CONCLUSION

A pharmacist-led MI intervention increased HepB vaccination rates among adult patients with diabetes. Community pharmacists can effectively provide vaccinations that require multiple doses to complete the vaccination series.

摘要

背景

2011 年,免疫实践咨询委员会建议对未接种过乙型肝炎(HepB)疫苗的成年糖尿病患者(19-59 岁)进行 HepB 疫苗接种。尽管有这些建议,但糖尿病患者的 HepB 疫苗接种覆盖率仍然很低。

目的

主要目的是确定社区药剂师主导的动机性访谈(MI)干预对以前未接种过 HepB 疫苗的成年糖尿病患者启动 HepB 疫苗接种的影响。次要目的是描述启动 HepB 疫苗接种的成年糖尿病患者完成 HepB 疫苗接种系列的情况。

方法

一项前瞻性、非随机、对照的群组试验在 58 家区域杂货店连锁店药房进行:共有 29 家药房在 MI 组,29 家药房在对照组。在为期 12 个月的项目前阶段收集药房位置级别的基线数据。MI 计划在 10 个月内进行。在整个研究期间,在每个 MI 药房位置处,在配药处理过程中生成警报,以识别合格患者。MI 由药剂师与患者在取药时进行面对面交谈组成。通过差异分析评估接受 MI 的患者与对照组患者之间主要结局(HepB 疫苗接种系列启动)的差异。对于系列完成,对启动 HepB 疫苗接种系列的患者进行随访,随访时间超过他们第一次接种 HepB 疫苗后 12 个月。

结果

与对照组(n=3640)相比,接受 MI 干预(n=1569)的合格个体中,HepB 疫苗接种率增加了 3.711%,差异具有统计学意义。在 MI 组中启动 HepB 疫苗接种的患者中,有 40 名患者(61.5%)完成了疫苗接种系列。

结论

药剂师主导的 MI 干预提高了成年糖尿病患者的 HepB 疫苗接种率。社区药剂师可以有效地提供需要多次接种才能完成疫苗接种系列的疫苗。

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