Ning N, Cai Y M, Weng H L, Wang L Z, Wen C L, Zhang J B, Ye X S, Chen Xiangsheng
Department of Sexually Transmitted Disease and Leprosy Control and Prevention,Shenzhen Center for Chronic Disease Control, Shenzhen 518020,China.
National Center for Sexually Transmitted Disease Control, Chinese Center for Disease Control and Prevention, Nanjing 210042, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2022 Sep 10;43(9):1436-1440. doi: 10.3760/cma.j.cn112338-20211015-00796.
To understand the prevalence of Chlamydia trachomatis (CT) infection and its associated factors among asymptomatic outpatients attending sexually transmitted disease (STD)-related clinics in Shenzhen and provide evidence for development of future interventions. From April 15 to May 16, 2018, a cross-sectional study was conducted and patients attending STD-related Clinics were recruited from 22 medical institutions in Nanshan, Luohu, Bao'an, Longgang, Yantian, and Longhua districts of Shenzhen. After the informed consent from each participant was obtained, social-demographic information was collected through a structured questionnaire and urine samples were collected for CT nucleic acid detection. In addition, logistic regression was used to explore associated factors of CT infection. In asymptomatic outpatients, the prevalence of CT infection was 7.16% (250/3 492). Being single (a=2.29, 95%:1.65-3.16), without registered Shenzhen residency (a=1.49, 95%:1.04-2.13), and without previous CT testing in the past year (a=2.04, 95%:1.03-4.05) were the risk factors of CT infection in asymptomatic outpatients. Among participants without registered Shenzhen residency, 89.25% (2 176/2 438) were college-degree or below, and 51.29% (1 255/2 447) were aged ≤30 years, and the risk of CT infection among those ≤30 years old was 1.73 times higher than those >30 years old (95%:1.28-2.34). The prevalence of CT infection was high among asymptomatic outpatients attending STD-related clinics in Shenzhen. Routine CT screening should be carried out for this population, especially for those with sexually active age, being single, with low educational level, and without previous CT testing in the past year. Also, raising their awareness of knowledge and adverse outcomes of CT infection should be considered to promote routine CT screening and timely treatment.
了解深圳性病相关门诊无症状就诊者沙眼衣原体（CT）感染的流行情况及其相关因素，为今后制定干预措施提供依据。2018年4月15日至5月16日，开展了一项横断面研究，从深圳南山、罗湖、宝安、龙岗、盐田和龙华区的22家医疗机构招募性病相关门诊的患者。在获得每位参与者的知情同意后，通过结构化问卷收集社会人口学信息，并采集尿液样本进行CT核酸检测。此外，采用logistic回归分析CT感染的相关因素。在无症状就诊者中，CT感染率为7.16%（250/3492）。单身（α=2.29，95%CI：1.65-3.16）、非深圳户籍（α=1.49，95%CI：1.04-2.13）以及过去一年未进行过CT检测（α=2.04，95%CI：1.03-4.05）是无症状就诊者CT感染的危险因素。在非深圳户籍参与者中，89.25%（2176/2438）为大专及以下学历，51.29%（1255/2447）年龄≤30岁，≤30岁者CT感染风险比>30岁者高1.73倍（95%CI：1.28-2.34）。深圳性病相关门诊无症状就诊者中CT感染率较高。应对该人群进行CT常规筛查，尤其是性活跃年龄、单身、文化程度低以及过去一年未进行过CT检测的人群。此外，应考虑提高他们对CT感染知识和不良后果的认识，以促进CT常规筛查和及时治疗。
