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新型冠状病毒肺炎(COVID-19)合并鼻眶毛霉菌病:一例报告

Rhino-orbital mucormycosis in COVID-19 (Corona Virus Disease): A case report.

作者信息

Kanaparti Alekhya, Alwala Adityamohan, Chaitanya Nallan Csk, Chikte Diksha, Jakkula Nithisha, Balaindra Monica

机构信息

Department of Oral and Maxillofacial Surgery, MNR Dental College and Hospital, Hyderabad, India.

Assistant professor, RAKCODS, Ras al Khaimah, UAE.

出版信息

J Family Med Prim Care. 2022 Jun;11(6):3321-3325. doi: 10.4103/jfmpc.jfmpc_1194_21. Epub 2022 Jun 30.

Abstract

BACKGROUND

Mucormycosis, often referred to as black fungus is being recognized as post treatment complication in COVID-19. A complex interaction of immune compromised state may lead to secondary fungal infections. Rhino-orbital mucormycosis, a rare fungal disease, involves the orbit, nose, and sinuses. If not intervened early it might progress with a fatal outcome. The present case report is a Rhino-orbital mucormycosis presentating as a secondary infection in COVID-19 patient and its management. A 51-year-old male patient diagnosed with COVID-19, developed periorbital odema of the left eye along with tooth pain. Nasal endoscopy, computed tomography, and Magnetic Resonance Imaging suggested Rhino-orbital mucormycosis. Surgical debridement followed by intravenous Amphotericin B was prescribed. After a week of follow-up, complete resolution of symptoms was noticed.

CONCLUSION

An early diagnosis and prompt management is the key to reduce morbidity and mortality in these patients. Prophylactic measures and judicious use of drugs may reduce the incidence of this opportunistic infection.

摘要

背景

毛霉病,通常被称为黑真菌病,正被视为新冠肺炎治疗后的并发症。免疫受损状态的复杂相互作用可能导致继发性真菌感染。鼻眶毛霉病是一种罕见的真菌疾病,累及眼眶、鼻子和鼻窦。如果不及早干预,病情可能会发展并导致致命后果。本病例报告是一例新冠肺炎患者出现的鼻眶毛霉病继发感染及其治疗情况。一名51岁男性患者被诊断为新冠肺炎,出现左眼眶周水肿和牙痛。鼻内镜检查、计算机断层扫描和磁共振成像提示为鼻眶毛霉病。处方了手术清创,随后静脉注射两性霉素B。经过一周的随访,症状完全缓解。

结论

早期诊断和及时治疗是降低这些患者发病率和死亡率的关键。预防措施和合理使用药物可能会降低这种机会性感染的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/54f7/9480762/e132daf548a6/JFMPC-11-3321-g001.jpg

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