来自兰科药用植物的二氢菲类化合物：综述

Qi Jia-Xin, Zhou Di, Jiang Wan-Ru, Chen Gang, Li Wei, Li Ning

Shenyang Key Laboratory for TCM Material Basis Study and Innovative Drug Development, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China.

Faculty of Pharmaceutical Sciences, Toho University, Chiba 274-8510, Japan.

Chin Herb Med. 2021 Oct 7;13(4):480-493. doi: 10.1016/j.chmed.2021.10.004. eCollection 2021 Oct.

The plants of Orchidaceae are widely distributed in the world, 47 species of which have been used as folk medicines with a long history. The tubers and stems of them exhibit diverse efficacy, including clearing heat and resolving toxin, moistening lung and relieving cough and promoting blood circulation. Since dihydrophenanthrenes were responsible for the medical purposes, the characteristic skeletons, pharmacological effects and clinical applications of dihydrophenanthrenes were summarized in this review, so as to provide a theoretical basis for the comprehensive study, development and application of DPs from medicinal plants of Orchidaceae.

兰科植物在世界范围内分布广泛，其中47种已被用作民间药物，历史悠久。它们的块茎和茎具有多种功效，包括清热解毒、润肺止咳和促进血液循环。由于二氢菲类化合物具有药用价值，本文综述了二氢菲类化合物的特征骨架、药理作用和临床应用，以期为兰科药用植物中二氢菲类化合物的综合研究、开发和应用提供理论依据。