Berardelli A, Inghilleri M, Formisano R, Accornero N, Manfredi M
J Neurol Neurosurg Psychiatry. 1987 Jun;50(6):732-7. doi: 10.1136/jnnp.50.6.732.
The muscle responses evoked by cortical and cervical stimulation in 11 patients with motor neuron disease were studied. The muscle potential in the abductor pollicis brevis, evoked by median nerve stimulation and the somatosensory potential evoked by wrist stimulation were also studied. In eight of 11 patients there was absence or increased central delay of the responses evoked by cortical stimulation. In four patients muscle responses on cervical stimulation and muscle action potentials on median nerve stimulation were also altered, indicating peripheral abnormalities. Somatosensory responses evoked by wrist stimulation were normal. Electrophysiological techniques are helpful in estimating the site of motor involvement in motor neuron disease.
对11例运动神经元病患者进行了皮质和颈部刺激诱发的肌肉反应研究。还研究了正中神经刺激诱发的拇短展肌肌肉电位以及腕部刺激诱发的体感电位。11例患者中有8例皮质刺激诱发的反应存在缺失或中枢延迟增加。4例患者颈部刺激时的肌肉反应及正中神经刺激时的肌肉动作电位也发生改变，提示存在周围神经异常。腕部刺激诱发的体感反应正常。电生理技术有助于评估运动神经元病中运动受累的部位。
