Cosi V, Poloni M, Mazzini L, Callieco R
J Neurol Neurosurg Psychiatry. 1984 Aug;47(8):857-61. doi: 10.1136/jnnp.47.8.857.
Forty five patients with amyotrophic lateral sclerosis were investigated, by means of somatosensory evoked potentials, in order to detect the presence of subclinical sensory changes. Cervical SEPs from the median nerve and cortical SEPs from the median and tibial nerve were recorded, showing a delay of N13 and subsequent components; the latency of the first constant cortical potential was also increased in many patients. Only the SEPs from the tibial nerve showed a decrease of amplitude. These results suggest a pathological slowing of conduction along the central sensory pathways in amyotrophic lateral sclerosis.
对45例肌萎缩侧索硬化症患者进行了体感诱发电位检查,以检测是否存在亚临床感觉变化。记录了正中神经的颈段体感诱发电位以及正中神经和胫神经的皮层体感诱发电位,结果显示N13及后续成分出现延迟;许多患者中首个恒定皮层电位的潜伏期期潜伏期也延长。只有胫神经的体感诱发电位显示波幅降低。这些结果提示肌萎缩侧索硬化症患者中枢感觉通路的传导出现病理性减慢。