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分析利伐沙班对腹腔镜根治性胃切除术后下肢深静脉血栓形成的预防作用。

Analysis of the Preventive Action of Rivaroxaban against Lower Extremity Deep Venous Thrombosis in Patients after Laparoscopic Radical Gastrectomy.

机构信息

Derpartment of Medical Oncology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000 Zhejiang, China.

Derpartment of Hematology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, 317000 Zhejiang, China.

出版信息

Comput Math Methods Med. 2022 Sep 10;2022:7140066. doi: 10.1155/2022/7140066. eCollection 2022.

DOI:10.1155/2022/7140066
PMID:36124169
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9482470/
Abstract

BACKGROUND

Gastric carcinoma (GC) is a common lethal cancer in the world. Patients are prone to develop lower extremity deep venous thrombosis (LEDVT) after laparoscopic radical gastrectomy (LRG), which threatens their life and health.

PURPOSE

This research is to clarify the preventive action of rivaroxaban (Riv) against LEDVT in patients undergoing LRG.

METHODS

A retrospective study was conducted on 70 patients with GC admitted for LRG between January 2019 and January 2022, including 40 patients (observation group) receiving Riv treatment and 30 patients (conventional group) treated with air wave pressure therapy apparatus. Quality of life, coagulation function, LEDVT formation, and complications were compared between groups.

RESULTS

The observation group had better recovery of life quality than the control group, along with more effective inhibition of coagulation disorders, less DVT formation, and fewer complications.

CONCLUSIONS

Compared with air wave pressure therapy apparatus, Riv has better preventive action against LEDVT in GC patients after LRG.

摘要

背景

胃癌(GC)是世界上常见的致命癌症。腹腔镜根治性胃切除术(LRG)后,患者易发生下肢深静脉血栓形成(LEDVT),威胁生命健康。

目的

本研究旨在阐明利伐沙班(Riv)对 LRG 患者 LEDVT 的预防作用。

方法

对 2019 年 1 月至 2022 年 1 月期间接受 LRG 的 70 例 GC 患者进行回顾性研究,包括接受 Riv 治疗的 40 例患者(观察组)和接受空气波压力治疗仪治疗的 30 例患者(常规组)。比较两组患者的生活质量、凝血功能、LEDVT 形成和并发症情况。

结果

观察组患者的生活质量恢复情况优于对照组,凝血功能障碍抑制效果更明显,DVT 形成更少,并发症也更少。

结论

与空气波压力治疗仪相比,Riv 对 LRG 后 GC 患者 LEDVT 的预防作用更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb28/9482470/bbfa380636ad/CMMM2022-7140066.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb28/9482470/b4ca13bf5729/CMMM2022-7140066.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb28/9482470/bbfa380636ad/CMMM2022-7140066.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb28/9482470/b4ca13bf5729/CMMM2022-7140066.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cb28/9482470/bbfa380636ad/CMMM2022-7140066.002.jpg

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