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比较 COVID-19 大流行期间所有肾脏替代治疗方式的 COVID-19 感染率和死亡率,以及家庭治疗的重要性。

Comparison of all renal replacement therapy modalities in terms of COVID-19 infection rate & mortality in the COVID-19 pandemic and importance of home therapies.

机构信息

Department of Nephrology, SBU. Yuksek Ihtisas Training and Research Hospital, Bursa, Turkey.

Department of Nephrology, Acıbadem Hospital, Bursa, Turkey.

出版信息

Ther Apher Dial. 2023 Jun;27(3):402-411. doi: 10.1111/1744-9987.13930. Epub 2022 Oct 6.

Abstract

BACKGROUND

This study aimed to compare the infection rate and infection-related mortality among all renal replacement therapies during the COVID-19 pandemics.

METHODS

One thousand three hundred thirty-six end-stage renal disease (ESRD) patients who had applied for renal replacement therapy between March 2020 and January 2021 were included in the study. COVID-19 infection and mortality rates were compared between patient groups.

RESULTS

The COVID-19 infection rate in the whole study group was 13.12% (n: 178). The highest infection rate was in the center hemodialysis, 16.33% (n: 139). There was no COVID-19 infection in home hemodialysis (HHD). Mortality rate was 2.87% (n: 39) in the whole cohort and 3.87% (n: 33) in center hemodialysis (CHD), 1.47% (n:5) in kidney transplant (Tx), and 0.81% (n: 1) in the peritoneal dialysis (PD) group. COVID-19 infection rate of home replacement therapy (HRT) (n: 39) patients was significantly lower than CHD (n: 139) (p < 0.001).

CONCLUSION

The COVID-19 infection rate and mortality were significantly lower than those of CHD in all home-based modalities subgroups.

摘要

背景

本研究旨在比较 COVID-19 大流行期间所有肾脏替代疗法的感染率和与感染相关的死亡率。

方法

纳入了 2020 年 3 月至 2021 年 1 月期间申请肾脏替代治疗的 1336 名终末期肾病(ESRD)患者。比较了患者组之间的 COVID-19 感染率和死亡率。

结果

全组 COVID-19 感染率为 13.12%(n:178)。中心血液透析组的感染率最高,为 16.33%(n:139)。家庭血液透析(HHD)组无 COVID-19 感染。全队列的死亡率为 2.87%(n:39),中心血液透析组(CHD)为 3.87%(n:33),肾移植(Tx)组为 1.47%(n:5),腹膜透析(PD)组为 0.81%(n:1)。家庭替代治疗(HRT)(n:39)患者的 COVID-19 感染率明显低于 CHD(n:139)(p<0.001)。

结论

所有家庭治疗模式亚组的 COVID-19 感染率和死亡率均明显低于 CHD。

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