Zafar Sana, Panthangi Venkatesh, Cyril Kurupp Adrienne R, Raju Anjumol, Luthra Gaurav, Shahbaz Mahrukh, Almatooq Halah, Foucambert Paul, Esbrand Faith D, Khan Safeera
Internal Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Pediatrics, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.
Cureus. 2022 Aug 16;14(8):e28071. doi: 10.7759/cureus.28071. eCollection 2022 Aug.
Pseudotumor cerebri syndrome (PTCS)/idiopathic intracranial hypertension (IIH) is a clinical presentation appertaining to signs/symptoms of raised intracranial pressure, like headache and papilledema. It is an uncommon but clinically significant cause of morbidity such as permanent vision loss. It is crucial to understand if idiopathic intracranial hypertension (IIH) is on the rise in adolescents, it is probably due to the rising prevalence of obesity worldwide. Our study aimed to find an association between obesity and IIH in adolescents. We utilized Preferred Reporting Items for Systematic Review and Meta-Analysis 2020 (PRISMA) guidelines to run this systematic review. Many publications related to the topic in the discussion were scrutinized through a comprehensive database search. We filtered them down to a final count of 10 articles after utilizing our inclusion/exclusion criteria and assessing the quality of work. In these final papers, we identified several possibilities to explain the link between obesity and IIH in adolescents. Overweight and obese adolescents were found to have a significantly increased risk of IIH development, with a more severe clinical picture seen in morbidly obese female patients.
假性脑瘤综合征（PTCS）/特发性颅内高压（IIH）是一种与颅内压升高的体征/症状相关的临床表现，如头痛和视乳头水肿。它是一种罕见但具有临床意义的发病原因，可导致诸如永久性视力丧失等疾病。了解青少年特发性颅内高压（IIH）是否呈上升趋势至关重要，这可能是由于全球肥胖患病率上升所致。我们的研究旨在发现青少年肥胖与IIH之间的关联。我们利用2020年系统评价和Meta分析的首选报告项目（PRISMA）指南进行了这项系统评价。通过全面的数据库搜索，对讨论中许多与该主题相关的出版物进行了审查。在使用我们的纳入/排除标准并评估工作质量后，我们将它们筛选至最终的10篇文章。在这些最终论文中，我们确定了几种可能性来解释青少年肥胖与IIH之间的联系。超重和肥胖青少年患IIH的风险显著增加，病态肥胖女性患者的临床表现更为严重。
