Suppr超能文献

拉克氏裂囊肿:一项单中心病例系列研究。

Rathke's cleft cysts: A single-center case series.

作者信息

Sharifi Guive, Amin Arsalan, Lotfinia Mahmoud, Hallajnejad Mohammad, Davoudi Zahra, Dilmaghani Nader Akbari, Mirghaed Omidvar Rezaei

机构信息

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.

Department of Neurosurgery, Medical Center Saarbruecken, Saarland, Germany.

出版信息

Surg Neurol Int. 2022 Aug 19;13:368. doi: 10.25259/SNI_1096_2021. eCollection 2022.

Abstract

BACKGROUND

Rathke's cleft cysts (RCCs) are common benign sellar or suprasellar lesions. The aim of this study is to report our experience on the management of 27 RCC cases.

METHODS

We retrospectively analyzed a series of 27 patients with symptomatic RCC who were referred to our department between January 2016 and January 2020. Data regarding patients' demographics, clinical evaluations, laboratory and neuroimaging findings, pathologic records, surgical treatment, and complications were extracted from our electronic database. All patients underwent RCC removal through a direct endoscopic endonasal transsphenoidal (EETS) approach, except for two cases.

RESULTS

Data of 27 patients (3 men and 24 women; mean age: 38 years) with symptomatic RCC were reviewed. The most common presenting symptom was headache, occurring in 20 (74.0%) patients. In 16 (59.2%) cases, the tumor was primarily located in the sella turcica. Nine (33.3%) cases exhibited a secondary suprasellar extension.

CONCLUSION

Our experience with RCC patients showed that EETS is a safe method of treatment, with minimal recurrence.

摘要

背景

拉克氏囊肿(RCCs)是常见的鞍区或鞍上良性病变。本研究的目的是报告我们处理27例拉克氏囊肿病例的经验。

方法

我们回顾性分析了2016年1月至2020年1月期间转诊至我科的一系列27例有症状的拉克氏囊肿患者。从我们的电子数据库中提取了有关患者人口统计学、临床评估、实验室和神经影像学检查结果、病理记录、手术治疗及并发症的数据。除2例患者外,所有患者均通过直接鼻内镜经蝶窦(EETS)入路切除拉克氏囊肿。

结果

对27例有症状的拉克氏囊肿患者(3例男性,24例女性;平均年龄:38岁)的数据进行了回顾。最常见的首发症状是头痛,20例(74.0%)患者出现该症状。16例(59.2%)病例中,肿瘤主要位于蝶鞍。9例(33.3%)病例出现继发性鞍上扩展。

结论

我们对拉克氏囊肿患者的治疗经验表明,鼻内镜经蝶窦入路是一种安全的治疗方法,复发率极低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/c9a069561107/SNI-13-368-g001.jpg

相似文献

1
Rathke's cleft cysts: A single-center case series.
Surg Neurol Int. 2022 Aug 19;13:368. doi: 10.25259/SNI_1096_2021. eCollection 2022.
2
Endoscopic Endonasal Approach in the Management of Rathke's Cleft Cysts.
PLoS One. 2015 Oct 16;10(10):e0139609. doi: 10.1371/journal.pone.0139609. eCollection 2015.
3
Characteristics of Rathke's cleft cyst based on cyst location with a primary focus on recurrence after resection.
J Neurosurg. 2015 Jun;122(6):1380-9. doi: 10.3171/2014.12.JNS14596. Epub 2015 Feb 13.
5
Rathke's cleft cyst marsupialization and repair with a free mucosal graft - Video case report and literature review.
Am J Otolaryngol. 2022 Sep-Oct;43(5):103519. doi: 10.1016/j.amjoto.2022.103519. Epub 2022 Jun 4.
7
Clinical, radiological and pathological features of patients with Rathke's cleft cysts: tumors that may recur.
J Clin Endocrinol Metab. 1997 Jul;82(7):2357-62. doi: 10.1210/jcem.82.7.4043.
8
Clinicopathologic Characteristics and Endoscopic Surgical Outcomes of Symptomatic Rathke's Cleft Cysts.
World Neurosurg. 2019 Dec;132:e208-e216. doi: 10.1016/j.wneu.2019.08.196. Epub 2019 Sep 4.
9
Recurrent Rathke's Cleft Cysts: Incidence and Surgical Management in a Tertiary Pituitary Center over 2 Decades.
Oper Neurosurg (Hagerstown). 2019 Jun 1;16(6):675-684. doi: 10.1093/ons/opy258.
10
Spontaneous pituitary adenoma occurring after resection of a Rathke's cleft cyst.
J Clin Neurosci. 2016 Nov;33:247-251. doi: 10.1016/j.jocn.2016.05.018. Epub 2016 Sep 3.

引用本文的文献

1
Chiasmatic syndrome caused by Rathke's cleft cyst: A case report.
Mol Clin Oncol. 2025 Mar 28;22(6):47. doi: 10.3892/mco.2025.2842. eCollection 2025 Jun.
2
Progress in investigating pituitary stalk lesions: A review.
Medicine (Baltimore). 2025 Jan 10;104(2):e41232. doi: 10.1097/MD.0000000000041232.
3
Natural history and surgical outcomes of Rathke's cleft cysts: a Spanish multicenter study.
Front Endocrinol (Lausanne). 2024 Jun 17;15:1413810. doi: 10.3389/fendo.2024.1413810. eCollection 2024.
4
Vertical triband flag sign for differential diagnosis of Rathke's cleft cyst.
World Neurosurg X. 2023 Dec 12;21:100260. doi: 10.1016/j.wnsx.2023.100260. eCollection 2024 Jan.

本文引用的文献

2
Surgical Management of Rathke Cleft Cysts.
World Neurosurg. 2017 Nov;107:276-284. doi: 10.1016/j.wneu.2017.07.164. Epub 2017 Aug 5.
3
Spontaneous Involution of Rathke's Cleft Cysts without Visual Symptoms.
Brain Tumor Res Treat. 2016 Oct;4(2):58-62. doi: 10.14791/btrt.2016.4.2.58. Epub 2016 Oct 31.
4
The Supraorbital Keyhole Approach to the Suprasellar and Supra-Intrasellar Rathke Cleft Cysts Under Pure Endoscopic Visualization.
World Neurosurg. 2016 Aug;92:120-125. doi: 10.1016/j.wneu.2016.04.121. Epub 2016 May 7.
5
Relationship Between Clinical Features and T2-Weighted Magnetic Resonance Images in Symptomatic Rathke Cleft Cysts.
World Neurosurg. 2016 Apr;88:421-427. doi: 10.1016/j.wneu.2015.10.018. Epub 2015 Oct 17.
6
Differentiation between Cystic Pituitary Adenomas and Rathke Cleft Cysts: A Diagnostic Model Using MRI.
AJNR Am J Neuroradiol. 2015 Oct;36(10):1866-73. doi: 10.3174/ajnr.A4387. Epub 2015 Aug 6.
7
Characteristics of Rathke's cleft cyst based on cyst location with a primary focus on recurrence after resection.
J Neurosurg. 2015 Jun;122(6):1380-9. doi: 10.3171/2014.12.JNS14596. Epub 2015 Feb 13.
8
Rathke's cleft cyst.
Handb Clin Neurol. 2014;124:255-69. doi: 10.1016/B978-0-444-59602-4.00017-4.
9
Rathke's cleft cyst recurrence after transsphenoidal surgery: a meta-analysis of 1151 cases.
J Clin Neurosci. 2014 Mar;21(3):378-85. doi: 10.1016/j.jocn.2013.07.008. Epub 2013 Oct 23.
10
Individualized surgical strategies for Rathke cleft cyst based on cyst location.
J Neurosurg. 2013 Dec;119(6):1437-46. doi: 10.3171/2013.8.JNS13777. Epub 2013 Sep 20.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验