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拉克氏裂囊肿:一项单中心病例系列研究。

Rathke's cleft cysts: A single-center case series.

作者信息

Sharifi Guive, Amin Arsalan, Lotfinia Mahmoud, Hallajnejad Mohammad, Davoudi Zahra, Dilmaghani Nader Akbari, Mirghaed Omidvar Rezaei

机构信息

Skull Base Research Center, Loghman Hakim Hospital, Shahid Beheshti University of Medical Science, Tehran, Iran.

Department of Neurosurgery, Medical Center Saarbruecken, Saarland, Germany.

出版信息

Surg Neurol Int. 2022 Aug 19;13:368. doi: 10.25259/SNI_1096_2021. eCollection 2022.

DOI:10.25259/SNI_1096_2021
PMID:36128136
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9479561/
Abstract

BACKGROUND

Rathke's cleft cysts (RCCs) are common benign sellar or suprasellar lesions. The aim of this study is to report our experience on the management of 27 RCC cases.

METHODS

We retrospectively analyzed a series of 27 patients with symptomatic RCC who were referred to our department between January 2016 and January 2020. Data regarding patients' demographics, clinical evaluations, laboratory and neuroimaging findings, pathologic records, surgical treatment, and complications were extracted from our electronic database. All patients underwent RCC removal through a direct endoscopic endonasal transsphenoidal (EETS) approach, except for two cases.

RESULTS

Data of 27 patients (3 men and 24 women; mean age: 38 years) with symptomatic RCC were reviewed. The most common presenting symptom was headache, occurring in 20 (74.0%) patients. In 16 (59.2%) cases, the tumor was primarily located in the sella turcica. Nine (33.3%) cases exhibited a secondary suprasellar extension.

CONCLUSION

Our experience with RCC patients showed that EETS is a safe method of treatment, with minimal recurrence.

摘要

背景

拉克氏囊肿(RCCs)是常见的鞍区或鞍上良性病变。本研究的目的是报告我们处理27例拉克氏囊肿病例的经验。

方法

我们回顾性分析了2016年1月至2020年1月期间转诊至我科的一系列27例有症状的拉克氏囊肿患者。从我们的电子数据库中提取了有关患者人口统计学、临床评估、实验室和神经影像学检查结果、病理记录、手术治疗及并发症的数据。除2例患者外,所有患者均通过直接鼻内镜经蝶窦(EETS)入路切除拉克氏囊肿。

结果

对27例有症状的拉克氏囊肿患者(3例男性,24例女性;平均年龄:38岁)的数据进行了回顾。最常见的首发症状是头痛,20例(74.0%)患者出现该症状。16例(59.2%)病例中,肿瘤主要位于蝶鞍。9例(33.3%)病例出现继发性鞍上扩展。

结论

我们对拉克氏囊肿患者的治疗经验表明,鼻内镜经蝶窦入路是一种安全的治疗方法,复发率极低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/52d55a3b3065/SNI-13-368-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/c9a069561107/SNI-13-368-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/935a3395009a/SNI-13-368-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/52d55a3b3065/SNI-13-368-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/c9a069561107/SNI-13-368-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/935a3395009a/SNI-13-368-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a9/9479561/52d55a3b3065/SNI-13-368-g003.jpg

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Surgical Management of Rathke Cleft Cysts.拉克氏裂囊肿的外科治疗
World Neurosurg. 2017 Nov;107:276-284. doi: 10.1016/j.wneu.2017.07.164. Epub 2017 Aug 5.
3
Spontaneous Involution of Rathke's Cleft Cysts without Visual Symptoms.无视觉症状的拉克氏裂囊肿自发消退
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Vertical triband flag sign for differential diagnosis of Rathke's cleft cyst.用于鉴别拉克氏囊肿的垂直三带征
World Neurosurg X. 2023 Dec 12;21:100260. doi: 10.1016/j.wnsx.2023.100260. eCollection 2024 Jan.
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Front Surg. 2023 Jan 5;9:1065316. doi: 10.3389/fsurg.2022.1065316. eCollection 2022.
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