Sahu Priya, Jain Swasti, Kaushal Manju
Department of Pathology, ABVIMS, and Dr. Ram Manohar Lohia Hospital, New Delhi, India.
Cytojournal. 2022 Sep 5;19:50. doi: 10.25259/Cytojournal_77_2020. eCollection 2022.
Kimura's disease (KD) is a chronic inflammatory disorder of unknown etiology, endemic in Asia. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head-and-neck region, blood and tissue eosinophilia, and elevated serum immunoglobulin (Ig) E levels. Many conditions including benign and malignant may mimic KD clinically. This study reports cytologic features of seven cases of KD which were studied and correlated with histology, Ig profile, and peripheral blood examination. KD shows a good response to medical treatment; hence, fine-needle aspiration cytology in conjunction with other laboratory findings lowers the need for additional biopsy procedures for early diagnosis as well as diagnosis of recurrent lesions.
木村病(KD)是一种病因不明的慢性炎症性疾病,在亚洲呈地方性流行。典型的临床表现包括三联征:无痛性单侧颈部淋巴结病或主要位于头颈部区域的皮下肿块、血液和组织嗜酸性粒细胞增多以及血清免疫球蛋白(Ig)E水平升高。许多情况(包括良性和恶性情况)在临床上可能与木村病相似。本研究报告了7例木村病的细胞学特征,并将其与组织学、免疫球蛋白谱和外周血检查结果进行了关联分析。木村病对药物治疗反应良好;因此,细针穿刺细胞学检查结合其他实验室检查结果可减少早期诊断以及复发病变诊断时额外活检程序的需求。