Dağalan Ziya, Koçak Ramazan, Daştan Arif, Nişancı Bilal
Department of Chemistry, Faculty of Sciences, Ataturk University, Erzurum 25240, Turkey.
Org Lett. 2022 Nov 18;24(45):8261-8264. doi: 10.1021/acs.orglett.2c02627. Epub 2022 Sep 21.
Herein, we report the first metal-free and molecular halogen reagent-free dihomohalogenation methodology by using Selectfluor as an oxidant and tetrabutylammonium bromide/chloride salts as a halogen source. This effective strategy provides various fluorine-free halogenated products easily in quantitative yields from alkenes, alkynes, and natural products.
在此，我们报道了首个无金属且无分子卤素试剂的二卤化方法，该方法使用Selectfluor作为氧化剂，四丁基溴化铵/氯化铵盐作为卤素源。这一有效策略能轻松地从烯烃、炔烃和天然产物中以定量产率得到各种无氟卤代产物。
