Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology School of Petrochemical Engineering, Changzhou University, Changzhou, Jiangsu, 213164, China.
Department of Chemistry and Chemical Biology, Indiana University Purdue University Indianapolis, Indianapolis, Indiana, 46202, USA.
Chem Asian J. 2020 Mar 16;15(6):729-741. doi: 10.1002/asia.202000011. Epub 2020 Mar 2.
Selectfluor, [1-chloromethyl-4-fluoro-1,4-diazoniabicyclo-[2.2.2]octane bis(tetrafluoroborate)], is not only an important electrophilic fluorinating agent but also a facile and efficient "fluorine-free" functional reagent in other organic reactions. In this Minireview, we will present a brief history of Selectfluor as a transition metal oxidant, fluorine cation and radical initiator in "fluorine-free" functionalizations over the last five years.
Selectfluor，[1-氯甲基-4-氟-1,4-二氮杂双环[2.2.2]辛烷双（四氟硼酸盐）]，不仅是一种重要的亲电氟化剂，而且在其他有机反应中也是一种简便高效的“无氟”功能试剂。在这篇综述中，我们将简要介绍 Selectfluor 作为过渡金属氧化剂、氟阳离子和自由基引发剂在过去五年中的“无氟”官能化反应中的应用历史。
