Baron H C, LaRaja R D, Rossi G, Atkinson D
J Vasc Surg. 1987 Aug;6(2):144-6. doi: 10.1067/mva.1987.avs0060144.
Nine hundred twelve patients received continuous epidural analgesia administered through an indwelling plastic catheter while undergoing vascular reconstruction of a lower extremity. During a portion of the operative event, the patients were totally, transiently anticoagulated with heparin. None of the patients had an untoward neurologic event that could be attributed to an epidural hematoma. Our results and those of others show that this form of regional analgesia is safe and far outweighs theoretic contraindications when anticoagulation with heparin is planned as a part of the operative event. In the patients with impaired pulmonary ventilation or a cardiac disorder, this method of analgesia offers many advantages over a general anesthetic, such as obviating aspiration pneumonitis and averting prolonged support in the recovery period after completion of the surgical procedure. The regional vasodilation ensuing from the epidural blockade is an additional advantage in patients undergoing vascular reconstruction for lower extremity ischemia.
912例患者在接受下肢血管重建手术时,通过留置的塑料导管接受持续硬膜外镇痛。在部分手术过程中,患者使用肝素进行了完全、短暂的抗凝。所有患者均未发生可归因于硬膜外血肿的不良神经事件。我们的结果以及其他人的结果表明,当计划将肝素抗凝作为手术过程的一部分时,这种区域镇痛形式是安全的,并且远远超过理论上的禁忌证。对于肺通气受损或患有心脏疾病的患者,这种镇痛方法相对于全身麻醉具有许多优势,例如避免吸入性肺炎以及避免在手术完成后的恢复期进行长时间的支持治疗。硬膜外阻滞引起的局部血管扩张对于接受下肢缺血血管重建手术的患者来说是另一个优势。