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尸检CT:确诊疑似心源性猝死病例的有用工具。

Post-mortem CT: A Useful Tool to Confirm a Case of Suspected Sudden Cardiac Death.

作者信息

Raj K Karthi Vignesh, Yadav Abhishek, G Gokul, Ranjan Amar, Gupta Sudhir K

机构信息

Forensic Medicine, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.

Forensic Medicine and Toxicology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.

出版信息

Cureus. 2022 Aug 15;14(8):e28021. doi: 10.7759/cureus.28021. eCollection 2022 Aug.

Abstract

Sudden cardiac death (SCD) is defined as the unexpected death of an individual, not due to any extracardiac cause, occurring within one hour of symptom onset or within 24 hours of last being seen in good health if the death is unwitnessed. Forensic pathologists routinely encounter several SCD cases in their practice. The presentation of such cases can be of two types; firstly, with typical signs and symptoms suggestive of cardiac pathology, and secondly, devoid of any presentation history. This history helps forensic pathologists look for relevant findings during the autopsy examination. The authors intend to explore the feasibility of using advanced radiological techniques like post-mortem CT (PMCT) in determining the cause of death through a minimally invasive approach. In the present case, a 65-year-old male was found unresponsive at his residence on the morning of his death. He had a history of dull chest pain for the past two days, which had resolved after he self-prescribed a few medications. The presenting complaint of chest pain had started the intervening night prior to his death. The deceased was a known case of hypertension and was not compliant with treatment, as stated by the relatives. He was declared as brought dead by the treating emergency medicine physician at the Fortis Flt. Lt. Rajan Dhall Hospital and the body was sent by the authorities to the mortuary of the Department of Forensic Medicine, AIIMS, New Delhi for autopsy examination since an autopsy should be conducted by a government hospital or institute by law. PMCT depicted an alternate hyperdense and hypodense region circumferentially surrounding the heart, indicating hemopericardium. It was followed by a traditional autopsy and histopathology examination, which confirmed the presence of hemopericardium and left ventricular rupture associated with acute coronary insufficiency. Such cases with an indicative history, circumstantial evidence, and PMCT findings can be considered for minimal invasive autopsy. If the external findings indicate the application of physical force, then an explorative dissection could be done. Therefore, we conclude that PMCT can be used as a reliable tool for determining the cause of death in SCDs on a case-to-case basis.

摘要

心脏性猝死(SCD)定义为个体意外死亡,并非由任何心外原因导致,症状发作后一小时内死亡,或在未被目睹死亡的情况下,最后一次被看到健康后24小时内死亡。法医病理学家在其工作中经常会遇到几例SCD病例。此类病例的表现可分为两种类型;首先,具有提示心脏病理的典型体征和症状,其次,没有任何发病史。这一病史有助于法医病理学家在尸检时寻找相关发现。作者打算探讨使用诸如死后CT(PMCT)等先进放射技术,通过微创方法确定死因的可行性。在本病例中,一名65岁男性于死亡当天上午被发现死于家中。他在过去两天有胸部隐痛病史,自行服用一些药物后症状缓解。胸痛主诉始于他死亡前一天的夜间。据亲属称,死者患有高血压,且不遵医嘱治疗。在富通空军中校拉詹·达尔医院,主治急诊内科医生宣布其已死亡,随后尸体被当局送往新德里全印医学科学研究所法医系停尸房进行尸检,因为法律规定尸检应由政府医院或机构进行。PMCT显示心脏周围有交替的高密度和低密度区域,提示心包积血。随后进行了传统尸检和组织病理学检查,证实存在心包积血以及与急性冠状动脉供血不足相关的左心室破裂。对于有指示性病史、间接证据和PMCT检查结果的此类病例,可考虑进行微创尸检。如果外部检查结果表明有外力作用的迹象,则可进行探索性解剖。因此,我们得出结论,PMCT可作为一种可靠工具,根据具体病例确定SCD的死因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcb8/9471983/3fa1c205197a/cureus-0014-00000028021-i01.jpg

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