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[搭载生物卫星“宇宙-1514”飞行的猴子颈总动脉血压和血流变化特征]

[Features of changes in blood pressure and blood flow in the common carotid artery of monkeys exposed aboard the biosatellite Cosmos-1514].

作者信息

Krotov V P, Sandler G, Badakva A M, Khaĭnz D, Magedov V S

出版信息

Kosm Biol Aviakosm Med. 1987 May-Jun;21(3):69-74.

PMID:3613499
Abstract

Preflight the rhesus-monkey Bion was implanted with sensors and transducers to measure blood pressure and linear flow velocity in the common carotid artery and to compare these parameters with central circulation. At the early flight stage blood pressure increased, blood flow decreased and resistance in the area grew. The last change can be regarded as a compensatory reaction that can provide rapid adaptation of regional circulation to changes in systemic circulation. At later flight stages blood pressure showed distinct circadian oscillations and blood flow, a significant increase when compared to the ground-based 36-hour control study. Regulatory mechanisms of the cardiovascular system changed to the greatest extent on flight day 2. This manifested as a decrease of the amplitude of circadian oscillations of the above circulation parameters. Signs of cardiovascular adaptation to the effects of microgravity were discerned on flight days 3 to 5.

摘要

对恒河猴“比昂”进行飞行前准备时,在其体内植入了传感器和换能器,以测量颈总动脉的血压和线性流速,并将这些参数与中心循环进行比较。在飞行早期阶段,血压升高,血流量减少,该区域的阻力增大。最后一个变化可被视为一种代偿反应,它能够使局部循环迅速适应体循环的变化。在飞行后期阶段,血压出现明显的昼夜节律振荡,血流量与地面36小时对照研究相比显著增加。心血管系统的调节机制在飞行第2天变化最大。这表现为上述循环参数的昼夜节律振荡幅度减小。在飞行第3至5天可看出心血管系统对微重力影响的适应迹象。

相似文献

1
[Features of changes in blood pressure and blood flow in the common carotid artery of monkeys exposed aboard the biosatellite Cosmos-1514].[搭载生物卫星“宇宙-1514”飞行的猴子颈总动脉血压和血流变化特征]
Kosm Biol Aviakosm Med. 1987 May-Jun;21(3):69-74.
2
[Hemodynamics in monkeys in the initial period of adaptation to weightlessness].[猴子在适应失重初期的血流动力学]
Kosm Biol Aviakosm Med. 1988 Sep-Oct;22(5):33-9.
3
Cardiovascular results from a rhesus monkey flown aboard the Cosmos 1514 spaceflight.搭载于宇宙1514号航天飞行中的恒河猴的心血管研究结果。
Aviat Space Environ Med. 1987 Jun;58(6):529-36.
4
[Intracranial pressure in monkeys during the flight of Cosmos-2229].[宇宙-2229飞行期间猴子的颅内压]
Aviakosm Ekolog Med. 1995;29(4):37-41.
5
[Effects of microgravity on indices of hemodynamics in monkeys during postural tests].[微重力对猴子在姿势测试期间血液动力学指标的影响]
Aviakosm Ekolog Med. 1997;31(2):14-20.
6
Analysis of aprotinin on the mean arterial pressure, carotid artery blood flow, and hindlimb vascular resistance in the live rat, and pulmonary vascular resistance in the isolated perfused rat lung.抑肽酶对活体大鼠平均动脉压、颈动脉血流量、后肢血管阻力以及离体灌注大鼠肺脏肺血管阻力的影响分析。
J Med. 1995;26(1-2):31-42.
7
[Characteristics of night sleep of monkeys on the ground and during space flight on "Kosmos-1667"].[地面及“宇宙-1667”号太空飞行期间猴子的夜间睡眠特征]
Kosm Biol Aviakosm Med. 1989 Sep-Oct;23(5):12-7.
8
[Experiments on rats exposed in the Cosmos 1667 biosatellite (goals, protocols, results)].
Kosm Biol Aviakosm Med. 1987 Jul-Aug;21(4):9-16.
9
Sleep-wake cycles in rhesus monkeys during Spacelab flight simulations.恒河猴在太空实验室飞行模拟期间的睡眠-觉醒周期。
J Gravit Physiol. 1995;2(1):P54-5.
10
[Circadian rhythms and temperature homeostasis in monkeys during a flight on the Kosmos 1514 biosatellite].[在“宇宙1514号”生物卫星飞行期间猴子的昼夜节律和体温调节]
Kosm Biol Aviakosm Med. 1987 Sep-Oct;21(5):14-8.

引用本文的文献

1
The cellular circadian oscillator--a fundamental biological mechanism corresponding to a geophysical periodicity.细胞昼夜节律振荡器——一种与地球物理周期性相对应的基本生物机制。
Int J Biometeorol. 1988 Sep;32(3):149-62. doi: 10.1007/BF01045273.